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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
folate receptor alpha
Summary
- Gene Symbol
-
- FOLR1
- Aliases
-
- FRĪ±
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endosome
- Folate-binding
- GPI-anchor
- Neurodegeneration
- Receptor
- Reference proteome
- Secreted
- Signal
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P15328 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of canonical Wnt signaling pathway | ||
| neural crest cell migration involved in heart formation | ||
| sperm-egg recognition | ||
| heart looping | ||
| fusion of sperm to egg plasma membrane involved in single fertilization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| ER to Golgi transport vesicle membrane |
|
|
| endoplasmic reticulum-Golgi intermediate compartment membrane |
|
|
| endosome | ||
| transport vesicle |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| folic acid receptor activity | ||
| folic acid binding | ||
| signaling receptor activity | ||
| protein binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14796 | Dubowitz syndrome | |
| DOID:1520 | colon carcinoma | |
| DOID:1574 | alcohol use disorder | |
| DOID:162 | cancer | |
| DOID:1790 | malignant mesothelioma | |
| DOID:1793 | pancreatic cancer | |
| DOID:1826 | epilepsy | |
| DOID:219 | colon cancer | |
| DOID:235 | colonic benign neoplasm | |
| DOID:2394 | ovarian cancer |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001249 | Intellectual disability |
| HP:0001250 | Seizure |
| HP:0002180 | Neurodegeneration |
| HP:0002376 | Developmental regression |
| Disease ID | Disease Name |
|---|---|
| OMIM:613068 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 394697 | Xenbase:XB-GENE-948101 | ||
| 103820749 | SERCA17347 | ||
| 100082740 | ORNAN14896 | ||
| 103117474 | ERIEU01841 | ||
| 100411818 | CALJA04658 | ||
| 105578795 | CERAT17517 | ||
| 102132305 | MACFA09773 | ||
| 718388 | MACMU10177 | ||
| 105468697 | MACNE12944 | ||
| 101001135 | PAPAN06917 |
