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RAB8B, member RAS oncogene family

Summary

Gene Symbol

Rab8b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

235442

PubChem

235442

Alliance of Genome Resources

MGI:2442982

Annotation

Keyword

Cell membrane
Cytoplasmic vesicle
Endosome
GTP-binding
Hydrolase
Magnesium
Membrane
Metal-binding
Methylation
Phosphoprotein
Prenylation
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P61028
Q0PD49

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
exocytosis	IBA
antigen processing and presentation	ISO
antigen processing and presentation	IEA
positive regulation of cell projection organization	ISO
positive regulation of cell projection organization	IEA

GO Hierarchy

biological process

immune system process [inference]

antigen processing and presentation

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis

endosomal transport [inference]

endocytic recycling

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

endosomal transport [inference]

endocytic recycling

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome membrane

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

protein localization to peroxisome [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

peroxisome organization [inference]

protein localization to peroxisome [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

cell junction organization [inference]

cell-substrate junction organization

export from cell [inference]

secretion by cell [inference]

exocytosis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

protein localization to peroxisome [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis

endosomal transport [inference]

endocytic recycling

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

secretion [inference]

secretion by cell [inference]

exocytosis

intracellular transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

endosomal transport [inference]

endocytic recycling

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome membrane

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

export from cell [inference]

secretion by cell [inference]

exocytosis

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

endosomal transport [inference]

endocytic recycling

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome membrane

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

endosomal transport [inference]

endocytic recycling

peroxisomal transport [inference]

peroxisomal membrane transport [inference]

protein import into peroxisome membrane

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

protein localization to peroxisome [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into peroxisome membrane

establishment of protein localization to organelle [inference]

establishment of protein localization to peroxisome [inference]

protein import into peroxisome membrane

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein import into peroxisome membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide hormone secretion [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide hormone secretion [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide hormone secretion [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide hormone secretion [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of peptide secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of multicellular organismal process [inference]

positive regulation of corticotropin secretion

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide hormone secretion [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide hormone secretion [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

positive regulation of secretion by cell [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of endocrine process [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of multicellular organismal process [inference]

positive regulation of corticotropin secretion

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

positive regulation of hormone secretion [inference]

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

regulation of peptide hormone secretion [inference]

regulation of corticotropin secretion [inference]

positive regulation of corticotropin secretion

positive regulation of peptide hormone secretion [inference]

positive regulation of corticotropin secretion

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
mitochondrion	HDA	18614015
endosome	IBA
peroxisomal membrane	ISO
peroxisomal membrane	IEA
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

microbody membrane [inference]

peroxisomal membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Golgi-associated vesicle [inference]

trans-Golgi network transport vesicle

transport vesicle [inference]

trans-Golgi network transport vesicle

exocytic vesicle [inference]

synaptic vesicle

coated vesicle [inference]

clathrin-coated vesicle [inference]

trans-Golgi network transport vesicle

endocytic vesicle [inference]

phagocytic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

perinuclear region of cytoplasm

cell pole [inference]

cell tip

presynapse

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
GTPase activity	IBA
GTPase activity	IEA
signaling receptor binding	ISO
signaling receptor binding	IEA
protein binding	IPI	17055430 18094055

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

signaling receptor binding

protein domain specific binding [inference]

TPR domain binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RAB

Functional Category

T: Signal transduction mechanisms
U: Intracellular trafficking, secretion, and vesicular transport

Displaying 1 entry
Gene Ontology
GTP binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Small GTPase

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements