GlyCosmos Portal

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IDA
vacuolar proton-transporting V-type ATPase, V0 domain	IEA
proton-transporting V-type ATPase complex		33065002
transmembrane transporter complex	IEA
plasma membrane	IBA IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

vacuolar proton-transporting V-type ATPase complex

proton-transporting two-sector ATPase complex, proton-transporting domain [inference]

proton-transporting V-type ATPase, V0 domain [inference]

vacuolar proton-transporting V-type ATPase, V0 domain

transmembrane transporter complex

catalytic complex [inference]

ATPase complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

vacuolar proton-transporting V-type ATPase complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ATPase binding	IBA
proton-transporting ATPase activity, rotational mechanism	IEA
protein binding	IPI	16415858

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

binding [inference]

protein binding

enzyme binding [inference]

ATPase binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000185344

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K02154

Name

V-type H+-transporting ATPase subunit a

References

Disease

Disease Ontology

Displaying entries **1 - 10** of **121** in total

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DO ID	Disease Name	Source
DOID:0040085	bacterial sepsis	DisGeNET
DOID:0050429	Hailey-Hailey disease	DisGeNET
DOID:0050453	lissencephaly	DisGeNET
DOID:0050570	congenital disorder of glycosylation type I	DisGeNET
DOID:0050589	inflammatory bowel disease	DisGeNET
DOID:0050777	Joubert syndrome	DisGeNET
DOID:0060192	Crohn's colitis	DisGeNET
DOID:0060249	scoliosis	DisGeNET DisGeNET
DOID:0060270	pontocerebellar hypoplasia type 2D	DisGeNET
DOID:0060276	pontocerebellar hypoplasia type 7	DisGeNET

The Human Phenotype Ontology

Displaying entries **41 - 50** of **114** in total

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HPO ID	HPO Term
HP:0001320	Cerebellar vermis hypoplasia
HP:0001321	Cerebellar hypoplasia
HP:0001339	Lissencephaly
HP:0001350	Slurred speech
HP:0001374	Congenital hip dislocation
HP:0001382	Joint hypermobility
HP:0001476	Delayed closure of the anterior fontanelle
HP:0001508	Failure to thrive
HP:0001511	Intrauterine growth retardation
HP:0001537	Umbilical hernia

Displaying **all 4** entries
Disease ID	Disease Name
OMIM:219200	autosomal recessive cutis laxa type 2A
ORPHA:357074	autosomal recessive cutis laxa type 2, classic type
OMIM:278250	wrinkly skin syndrome
ORPHA:2834	wrinkly skin syndrome

PubChem Disease

GHR Health Conditions

Cutis laxa

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Cutis laxa

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **11 - 20** of **106** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	561469	ZFIN:ZDB-GENE-091113-4	DANRE01237
Astyanax mexicanus	103042490		ASTMX12852
Ictalurus punctatus	108255708		ICTPU16915
Ictalurus punctatus	108277010		ICTPU08557
Electrophorus electricus	113583015		ELEEL30740
Esox lucius	105014861		ESOLU41003
Salmo salar	106563184		SALSA16462
Salmo salar	106580324		SALSA76625
Salmo trutta	115159435		SALTR69159
Salmo trutta	115164441		SALTR60280

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements