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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

leukocyte immunoglobulin like receptor A4

Summary

Gene Symbol

LILRA4

Organism

Homo sapiens (human)

External Links

NCBI Gene

23547

PubChem

23547

Alliance of Genome Resources

HGNC:15503

JoGo

LILRA4

TogoVar

LILRA4

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Innate immunity
Nitration
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P59901	CD85 antigen-like family member G Immunoglobulin-like transcript 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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Last »
GO Term	Evidence Code	PMID
immune response-regulating signaling pathway	IBA
cytokine-mediated signaling pathway	IBA
negative regulation of interferon-alpha production	IMP	16735691
negative regulation of tumor necrosis factor production	IMP	16735691
negative regulation of toll-like receptor 7 signaling pathway	IMP	16735691

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cytokine-mediated signaling pathway

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

negative regulation of interferon-alpha production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

negative regulation of interferon-alpha production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

negative regulation of interferon-alpha production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway [inference]

Fc-epsilon receptor signaling pathway

cytokine-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 7 signaling pathway [inference]

negative regulation of toll-like receptor 7 signaling pathway

regulation of toll-like receptor 9 signaling pathway [inference]

negative regulation of toll-like receptor 9 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

negative regulation of interferon-alpha production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

regulation of type I interferon production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

negative regulation of interferon-alpha production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

negative regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of type I interferon production [inference]

negative regulation of interferon-alpha production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor production

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	16735691
plasma membrane	IBA
Fc-epsilon receptor I complex	IDA	16735691

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

Fc receptor complex [inference]

Fc-epsilon receptor I complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IPI	16735691
protein binding	IPI	19564354
coreceptor activity	IDA	16735691
inhibitory MHC class I receptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

MHC class I receptor activity [inference]

inhibitory MHC class I receptor activity

coreceptor activity

immune receptor activity [inference]

MHC class I receptor activity [inference]

inhibitory MHC class I receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

leukocyte immunoglobulin-like receptor subfamily B member 3

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
cell surface receptor signaling pathway
cytokine-mediated signaling pathway
inhibitory MHC class I receptor activity

Displaying **all 4** entries
InterPro
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Immunoglobulin

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026