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hyaluronidase 4

Summary

Gene Symbol

HYAL4

Organism

Homo sapiens (human)

External Links

NCBI Gene

23553

HGNC

5323

KEGG Gene ID

hsa:23553

PubChem

23553

Alliance of Genome Resources

HGNC:5323

Annotation

Keyword

Disulfide bond
EGF-like domain
Glycoprotein
Glycosidase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2M3T9	Chondroitin sulfate endo-beta-N-acetylgalactosaminidase Chondroitin sulfate hydrolase Hyaluronoglucosaminidase-4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycosaminoglycan catabolic process	TAS	10493834
hyaluronan catabolic process	IBA
carbohydrate metabolic process	IEA
chondroitin sulfate catabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

catabolic process [inference]

cellular catabolic process [inference]

sulfur compound catabolic process [inference]

chondroitin sulfate catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

sulfur compound catabolic process [inference]

chondroitin sulfate catabolic process

cellular catabolic process [inference]

sulfur compound catabolic process [inference]

chondroitin sulfate catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

hyaluronan metabolic process [inference]

hyaluronan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

cellular process [inference]

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate catabolic process

sulfur compound catabolic process [inference]

chondroitin sulfate catabolic process

cellular catabolic process [inference]

sulfur compound catabolic process [inference]

chondroitin sulfate catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cell surface	IEA
membrane	IEA
cytoplasmic vesicle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying 1 entry
GO Term	Evidence Code	PMID
hyalurononglucosaminidase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

hexosaminidase activity [inference]

hyalurononglucosaminidase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01197

Name

hyaluronoglucosaminidase [EC:3.2.1.35]

References

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07825	3.2.1.35	G34586BV	G92988PL
R07824	3.2.1.35	G81393WR	G92988PL
R10905	3.2.1.35	G16235VG	G16235VG G93263XO

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:5389	oxyphilic adenoma	DisGeNET DisGeNET
DOID:6245	renal oncocytoma	DisGeNET

Ortholog

Displaying entries **1 - 10** of 93 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	174383	WB:WBGene00011923
Latimeria chalumnae	102354923		LATCH01129
Danio rerio	108181664	ZFIN:ZDB-GENE-061220-9	DANRE27705
Ictalurus punctatus	108274420		ICTPU06322
Electrophorus electricus	113583177		ELEEL06726
Esox lucius	105009887		ESOLU56019
Salmo salar	106561029		SALSA08207
Salmo salar	106584561		SALSA84101
Salmo trutta	115192733		SALTR30915
Salmo trutta	115197788		SALTR12280