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dynein cytoplasmic 1 light intermediate chain 1

Summary

Gene Symbol

Dync1li1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

235661

PubChem

235661

Alliance of Genome Resources

MGI:2135610

Annotation

Keyword

ATP-binding
Centromere
Chromosome
Cytoskeleton
Direct protein sequencing
Dynein
Endosome
Kinetochore
Membrane
Microtubule
Mitosis
Motor protein
Phosphoprotein
Reference proteome
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8R1Q8	Dynein light chain A Dynein light intermediate chain 1, cytosolic
Q3TWG5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IBA
microtubule-based movement	ISS	11243854
microtubule-based movement	ISO
microtubule-based movement	IBA
regulation of centrosome cycle	ISO

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

vesicle-mediated transport between endosomal compartments [inference]

early endosome to recycling endosome transport

cell division

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

vesicle-mediated transport between endosomal compartments [inference]

early endosome to recycling endosome transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

response to nerve growth factor [inference]

cellular response to nerve growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

vesicle-mediated transport between endosomal compartments [inference]

early endosome to recycling endosome transport

intracellular transport [inference]

endosomal transport [inference]

vesicle-mediated transport between endosomal compartments [inference]

early endosome to recycling endosome transport

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport [inference]

vesicle-mediated transport between endosomal compartments [inference]

early endosome to recycling endosome transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

vesicle-mediated transport between endosomal compartments [inference]

early endosome to recycling endosome transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of spindle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of mitotic spindle checkpoint [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of spindle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of mitotic spindle checkpoint [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of spindle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of mitotic spindle checkpoint [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of microtubule-based process [inference]

regulation of centrosome cycle

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of chromosome organization [inference]

regulation of sister chromatid segregation [inference]

regulation of mitotic sister chromatid segregation [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of nuclear division [inference]

regulation of mitotic nuclear division [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of centrosome cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of mitotic spindle checkpoint [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of cell cycle process [inference]

regulation of mitotic nuclear division [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of centrosome cycle

regulation of chromosome segregation [inference]

regulation of sister chromatid segregation [inference]

regulation of mitotic sister chromatid segregation [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of chromosome separation [inference]

regulation of mitotic sister chromatid separation [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle process [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of cell cycle phase transition [inference]

regulation of cell cycle checkpoint [inference]

regulation of spindle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of mitotic spindle checkpoint [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle checkpoint [inference]

positive regulation of spindle checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

regulation of mitotic cell cycle spindle assembly checkpoint [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of mitotic cell cycle spindle assembly checkpoint

regulation of vesicle-mediated transport

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
kinetochore	ISS
kinetochore	ISO
spindle pole	ISS
spindle pole	ISO
late endosome	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

cytoplasmic dynein complex

catalytic complex [inference]

dynein complex [inference]

cytoplasmic dynein complex

cellular anatomical entity [inference]

spindle pole

microtubule organizing center [inference]

centrosome

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

recycling endosome membrane

endocytic vesicle membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

recycling endosome membrane

endocytic vesicle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular non-membrane-bounded organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
microtubule motor activity	ISS	11243854
ATP binding	IEA
GDP binding	ISO
GDP binding	IEA
protein-macromolecule adaptor activity	ISO

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GDP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GDP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GDP binding

ion binding [inference]

anion binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GDP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GDP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GDP binding

molecular adaptor activity

protein-macromolecule adaptor activity

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytoplasmic dynein 1 light intermediate chain 1

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
dynein heavy chain binding
microtubule cytoskeleton organization
microtubule-based movement
nucleotide binding

Displaying **all 3** entries
InterPro
Dynein 1 light intermediate chain
Dynein family light intermediate chain
P-loop containing nucleoside triphosphate hydrolase

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements