GlyCosmos Portal

Submissions

potassium voltage-gated channel subfamily E regulatory subunit 5

Summary

Gene Symbol

KCNE5

Organism

Homo sapiens (human)

External Links

NCBI Gene

23630

PubChem

23630

Alliance of Genome Resources

HGNC:6241

JoGo

KCNE5

TogoVar

KCNE5

Annotation

Keyword

Alport syndrome
Deafness
Elliptocytosis
Glycoprotein
Intellectual disability
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UJ90	AMME syndrome candidate gene 2 protein Potassium channel subunit beta MiRP4 Potassium voltage-gated channel subfamily E member 1-like protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
regulation of heart contraction	IMP	18313602
cardiac muscle contraction	IMP	18313602
regulation of membrane repolarization	IDA	21493962
regulation of ventricular cardiac muscle cell membrane repolarization	IMP	21493962
regulation of ventricular cardiac muscle cell membrane repolarization	IBA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion export across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion export across plasma membrane

export across plasma membrane [inference]

potassium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

potassium ion export across plasma membrane

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction [inference]

cardiac muscle contraction

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport [inference]

potassium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion export across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion export across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion export across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion export across plasma membrane

export across plasma membrane [inference]

potassium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

potassium ion export across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of potassium ion transmembrane transport

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of potassium ion transport [inference]

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport

regulation of potassium ion transmembrane transport

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of potassium ion transmembrane transport

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of potassium ion transmembrane transport

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of potassium ion transport [inference]

positive regulation of potassium ion transmembrane transport

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

negative regulation of transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

negative regulation of potassium ion transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of potassium ion transmembrane transport

regulation of potassium ion export across plasma membrane [inference]

negative regulation of potassium ion export across plasma membrane

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of potassium ion transmembrane transport

negative regulation of cellular process [inference]

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of cation transmembrane transport [inference]

negative regulation of potassium ion transmembrane transport

negative regulation of potassium ion export across plasma membrane

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

cardiac conduction [inference]

regulation of heart rate by cardiac conduction

regulation of membrane repolarization

regulation of cardiac muscle cell membrane repolarization [inference]

regulation of biological quality [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

regulation of membrane potential [inference]

action potential [inference]

cardiac muscle cell action potential [inference]

cardiac muscle cell action potential involved in contraction [inference]

regulation of membrane repolarization

regulation of cardiac muscle cell membrane repolarization [inference]

membrane repolarization [inference]

membrane repolarization during action potential

membrane repolarization during cardiac muscle cell action potential [inference]

membrane repolarization during ventricular cardiac muscle cell action potential

cardiac muscle cell membrane repolarization [inference]

membrane repolarization during cardiac muscle cell action potential [inference]

membrane repolarization during ventricular cardiac muscle cell action potential

ventricular cardiac muscle cell membrane repolarization [inference]

membrane repolarization during ventricular cardiac muscle cell action potential

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	20533308
voltage-gated potassium channel complex	IDA	12324418 21493962
voltage-gated potassium channel complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
voltage-gated potassium channel activity
delayed rectifier potassium channel activity	IBA
protein binding	IPI	20533308 32296183
potassium channel regulator activity	IDA	12324418 18313602 21493962
potassium channel regulator activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [inference]

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

binding [inference]

protein binding

transmembrane transporter binding

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

potassium channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Potassium voltage-gated channel subfamily E regulatory beta subunit 5

Functional Category

G: Carbohydrate transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
delayed rectifier potassium channel activity
monoatomic ion transport
potassium channel regulator activity
regulation of heart rate by cardiac conduction
regulation of ventricular cardiac muscle cell membrane repolarization
transmembrane transporter binding
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
voltage-gated potassium channel activity

Displaying 1 entry
InterPro
Potassium channel, voltage-dependent, beta subunit, KCNE

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements