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solute carrier family 9 (sodium/hydrogen exchanger), member 7

Summary

Gene Symbol

Slc9a7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

236727

PubChem

236727

Alliance of Genome Resources

MGI:2444530

Annotation

Keyword

Alternative splicing
Antiport
Cell membrane
Endosome
Glycoprotein
Golgi apparatus
Phosphoprotein
Potassium transport
Reference proteome
Sodium transport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BLV3	Na(+)/H(+) exchanger 7 Solute carrier family 9 member 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
regulation of Golgi lumen acidification	ISO ISS
potassium ion transmembrane transport	IBA IEA
regulation of intracellular pH	IBA
sodium ion import across plasma membrane	IBA
regulation of pH	ISO ISS

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

monoatomic cation homeostasis [inference]

regulation of pH

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

sodium ion import across plasma membrane

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biological regulation [inference]

regulation of pH

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

regulation of biological process [inference]

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

regulation of biological quality [inference]

regulation of intracellular pH

regulation of cellular pH reduction [inference]

regulation of Golgi lumen acidification

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
recycling endosome	IBA
membrane	ISO ISS
intracellular membrane-bounded organelle	ISO
plasma membrane	IBA ISO ISS
trans-Golgi network	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

recycling endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

recycling endosome membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
potassium:proton antiporter activity	IBA ISO ISS
sodium:proton antiporter activity	IBA ISO ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

sodium/hydrogen exchanger 7

Functional Category

L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
monoatomic ion transport
potassium
regulation of intracellular pH
regulation of pH
sodium ion transmembrane transport

Displaying **all 4** entries
InterPro
Cation/H+ exchanger, CPA1 family
Cation/H+ exchanger
Na+/H+ exchanger
Sodium/hydrogen exchanger 6/7/9

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111844	X-linked intellectual developmental disorder 108	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **100** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	33939		FB:FBgn0028703
Homo sapiens	84679		HGNC:17123	HUMAN100358
Rattus norvegicus	317170	10116_1:005584	RGD:1561385	RATNO44351
Pan troglodytes	465595			PANTR45866
Bos taurus	522505			BOVIN36967
Danio rerio	554532		ZFIN:ZDB-GENE-050913-8
Canis lupus familiaris	609144			CANLF19718
Macaca mulatta	710906			MACMU48644
Saccharomyces cerevisiae S288C	852066		SGD:S000002864
Monodelphis domestica	100011742			MONDO32172