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ADAM metallopeptidase with thrombospondin type 1 motif 19
Summary
- Gene Symbol
-
- Adamts19
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P59509 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| aortic valve morphogenesis | ||
| aortic valve morphogenesis | ||
| mitral valve morphogenesis | ||
| pulmonary valve morphogenesis | ||
| tricuspid valve morphogenesis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular matrix |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- thrombospondin
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| extracellular matrix organization |
| metalloendopeptidase activity |
| proteolysis |
| serine-type endopeptidase inhibitor activity |
| InterPro |
|---|
| ADAMTS/ADAMTS-like, Spacer 1 |
| ADAMTS/ADAMTS-like |
| PLAC |
| Thrombospondin type-1 (TSP1) repeat superfamily |
| Thrombospondin type-1 (TSP1) repeat |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:62 | aortic valve disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 11173 | FB:FBgn0029791 | ||
| 81792 | FB:FBgn0029791 | ||
| 108153 | FB:FBgn0029791 | ||
| 170691 | FB:FBgn0029791 | ||
| 170692 | FB:FBgn0029791 | ||
| 171019 | Xenbase:XB-GENE-980450 | HUMAN80568 | |
| 208936 | FB:FBgn0029791 | ||
| 239337 | FB:FBgn0029791 | ||
| 240322 | Xenbase:XB-GENE-980450 | ||
| 315879 | FB:FBgn0029791 |
