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Guidelines

MIRAGE

sarcoglycan, beta (dystrophin-associated glycoprotein)

Summary

Gene Symbol

Sgcb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

24051

PubChem

24051

Alliance of Genome Resources

MGI:1346523

Annotation

Keyword

Cell membrane
Cytoskeleton
Disulfide bond
Glycoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P82349	43 kDa dystrophin-associated glycoprotein

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
muscle organ development	IEA
metabolic process	IMP	19494113
response to glucose	IMP	19494113
gene expression	IMP	19494113
glucose homeostasis	IMP	19494113

GO Hierarchy

biological process

metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell development [inference]

muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell development [inference]

muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

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GO Term	Evidence Code	PMID
cytoplasm	IEA
cytoskeleton	IEA
plasma membrane	TAS	10448073
plasma membrane	IDA	10481911 16524571 17164264
dystrophin-associated glycoprotein complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

glycoprotein complex [inference]

dystrophin-associated glycoprotein complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

sarcolemma

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	16524571

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sarcoglycan beta

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
muscle organ development

Displaying **all 2** entries
InterPro
Beta-sarcoglycan
Sarcoglycan complex subunit protein

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110279	autosomal recessive limb-girdle muscular dystrophy type 2E	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6443	Xenbase:XB-GENE-943307	HUMAN75546
Xenopus tropicalis	24051	Xenbase:XB-GENE-943307
Pan troglodytes	461332		PANTR33991
Danio rerio	559788		DANRE19811
Canis lupus familiaris	611066		CANLF03386
Rattus norvegicus	680229		RATNO07887
Macaca mulatta	698988		MACMU36111
Macaca mulatta	702684		MACMU36111
Oryctolagus cuniculus	100009208		RABIT08058
Monodelphis domestica	100018476		MONDO27548

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025