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MIRAGE
leucine rich repeat containing 8A VRAC subunit A
Summary
- Gene Symbol
-
- Lrrc8a
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ion channel
- Leucine-rich repeat
- Lysosome
- Phosphoprotein
- Reference proteome
- Repeat
- Spermatogenesis
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q80WG5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic anion transport | ||
| cell volume homeostasis | ||
| cell volume homeostasis | ||
| response to osmotic stress | ||
| response to osmotic stress |
GO Hierarchy
biological process
cellular process [inference]
localization [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasm | ||
| lysosomal membrane | ||
| lysosomal membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| volume-sensitive anion channel activity | ||
| volume-sensitive anion channel activity | ||
| volume-sensitive anion channel activity | ||
| volume-sensitive anion channel activity | ||
| monoatomic anion channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- volume-regulated anion channel subunit LRRC8A
- Functional Category
-
- I: Lipid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| monoatomic ion transport |
| InterPro |
|---|
| LRRC8, pannexin-like TM region |
| Leucine-rich repeat domain superfamily |
| Leucine-rich repeat, typical subtype |
| Leucine-rich repeat |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 108279169 | ICTPU11039 | ||
| 108283033 | CEBIM26373 | ||
| 108423682 | PYGNA04656 | ||
| 108512835 | RHIBE17604 | ||
| 109064327 | CYPCA99400 | ||
| 109098616 | CYPCA13737 | ||
| 109313914 | CROPO20123 | ||
| 109525242 | HIPCM09713 | ||
| 111236172 | SERDU23435 | ||
| 111236468 | SERDU23435 |
