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MIRAGE
FtsJ RNA 2'-O-methyltransferase 1

Summary
Gene Symbol
  • FTSJ1
Organism
Homo sapiens (human)
NCBI Gene
24140
KEGG Gene ID
PubChem
24140
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cytoplasm
  • Disease variant
  • Intellectual disability
  • Methyltransferase
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • S-adenosyl-L-methionine
  • tRNA processing
Proteins
Displaying all 5 entries
UniProt Protein Name
B7Z4K4
B3KN91
  • 2'-O-ribose RNA methyltransferase TRM7 homolog
  • Protein ftsJ homolog 1
A0A024QYX5
A0A0S2Z5C9
  • 2'-O-ribose RNA methyltransferase TRM7 homolog
  • Protein ftsJ homolog 1
Q9UET6
  • 2'-O-ribose RNA methyltransferase TRM7 homolog
  • Protein ftsJ homolog 1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 14 in total
GO Term Evidence Code PMID
tRNA nucleoside ribose methylation
tRNA nucleoside ribose methylation
wobble position ribose methylation
wobble position ribose methylation
cytoplasmic translation
GO Hierarchy
Displaying entries 6 - 10 of 12 in total
GO Term Evidence Code PMID
obsolete tRNA 2'-O-methyltransferase activity
tRNA (cytidine(32)-2'-O-ribose)-methyltransferase activity
tRNA (cytidine(32)-2'-O-ribose)-methyltransferase activity
tRNA (guanosine(34)-2'-O-ribose)-methyltransferase activity
tRNA (guanosine(34)-2'-O-ribose)-methyltransferase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0112034 non-syndromic X-linked intellectual disability 9
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026