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ceramide synthase 6

Summary

Gene Symbol

Cers6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

241447

PubChem

241447

Alliance of Genome Resources

MGI:2442564

Annotation

Keyword

3D-structure
Acetylation
DNA-binding
Endoplasmic reticulum
Glycoprotein
Homeobox
Inflammatory response
Lipid biosynthesis
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
H3BL08
Q8C172	LAG1 longevity assurance homolog 6 Sphingoid base N-palmitoyltransferase CERS6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
inflammatory response	IEA
sphingolipid biosynthetic process	IDA	15823095
ceramide biosynthetic process	ISO
ceramide biosynthetic process	IDA	15823095 26620563
ceramide biosynthetic process	IMP	23760501

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

amide biosynthetic process [inference]

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process

ceramide biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

ceramide biosynthetic process

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of glial cell apoptotic process [inference]

positive regulation of oligodendrocyte apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of glial cell apoptotic process [inference]

positive regulation of glial cell apoptotic process [inference]

positive regulation of oligodendrocyte apoptotic process

regulation of oligodendrocyte apoptotic process [inference]

positive regulation of oligodendrocyte apoptotic process

positive regulation of apoptotic process [inference]

positive regulation of glial cell apoptotic process [inference]

positive regulation of oligodendrocyte apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of glial cell apoptotic process [inference]

positive regulation of oligodendrocyte apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of glial cell apoptotic process [inference]

positive regulation of oligodendrocyte apoptotic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	15823095
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
DNA binding	IEA
protein binding	IPI	26620563
sphingosine N-acyltransferase activity	ISO
sphingosine N-acyltransferase activity	IDA	15823095
sphingosine N-acyltransferase activity	IMP	23760501

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

N-acyltransferase activity [inference]

sphingosine N-acyltransferase activity

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ceramide synthase

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ceramide biosynthetic process
lipid metabolic process
sphingolipid metabolic process
sphingosine N-acyltransferase activity
transferase activity

Displaying **all 4** entries
InterPro
Homeobox domain
Homeobox-like domain superfamily
Sphingosine N-acyltransferase Lag1/Lac1-like
TRAM/LAG1/CLN8 homology domain

Ortholog

Displaying entries **31 - 40** of **103** in total

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Species	Gene ID	Orthologous MAtrix
Cricetulus griseus	100761613	CRIGR01323
Otolemur garnettii	100965109	OTOGA07531
Pan paniscus	100985038	PANPA25993
Papio anubis	101010164	PAPAN01488
Saimiri boliviensis boliviensis	101042109	SAIBB03608
Takifugu rubripes	101069883	TAKRU25716
Felis catus	101084386	FELCA20470
Ovis aries	101122252	SHEEP09447
Gorilla gorilla gorilla	101126713	GORGO26525
Oryzias latipes	101156449	ORYLA09839