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MIRAGE
angiotensinogen
Summary
- Gene Symbol
-
- Agt
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Proteomics identification
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Vasoconstrictor
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8L2UK05 |
|
| A6KJ10 |
|
| P01015 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| MAPK cascade | ||
| ovarian follicle rupture | ||
| blood vessel development | ||
| branching involved in ureteric bud morphogenesis | ||
| positive regulation of cytokine production |
GO Hierarchy
- positive regulation of membrane hyperpolarization
- regulation of transmission of nerve impulse
biological process
cellular process [inference]
multicellular organismal process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of organic acid transport [inference]
regulation of transmembrane transport [inference]
regulation of secretion [inference]
positive regulation of transport [inference]
regulation of amine transport [inference]
regulation of cellular localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
positive regulation of transport [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase inhibitor activity | ||
| serine-type endopeptidase inhibitor activity | ||
| hormone activity | ||
| hormone activity | ||
| hormone activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Angiotensinogen
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| regulation of apoptotic process |
| regulation of systemic arterial blood pressure by renin-angiotensin |
| serine-type endopeptidase inhibitor activity |
| InterPro |
|---|
| Angiotensinogen |
| Serpin domain |
| Serpin family |
| Serpin superfamily, domain 1 |
| Serpin superfamily, domain 2 |
| Serpin superfamily |
| Serpin, conserved site |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080322 | polycystic kidney disease | |
| DOID:10763 | hypertension | |
| DOID:10808 | gastric ulcer | |
| DOID:11446 | sciatic neuropathy | |
| DOID:1875 | impotence | |
| DOID:1936 | atherosclerosis | |
| DOID:3770 | pulmonary fibrosis | |
| DOID:5844 | myocardial infarction | |
| DOID:6432 | pulmonary hypertension | |
| DOID:8947 | diabetic retinopathy |
