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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

aldo-keto reductase family 1 member B1

Summary

Gene Symbol

Akr1b1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24192

PubChem

24192

Alliance of Genome Resources

RGD:2092

Annotation

Keyword

Acetylation
Cytoplasm
Direct protein sequencing
Lipid metabolism
NADP
Oxidoreductase
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P07943	Aldehyde reductase Aldose reductase
A6IEL2	Aldose reductase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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Last »
GO Term	Evidence Code	PMID
retinoid metabolic process	ISS
retinoid metabolic process	ISO
tissue homeostasis	IMP	21376710
epithelial cell maturation	ISO
renal water homeostasis	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

secondary metabolic process [inference]

polyketide metabolic process [inference]

hormone metabolic process [inference]

retinol metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

primary alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

tertiary alcohol metabolic process [inference]

doxorubicin metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process

hexose metabolic process [inference]

fructose metabolic process [inference]

fructose biosynthetic process

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

polyketide metabolic process [inference]

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

olefinic compound metabolic process [inference]

retinol metabolic process

carbohydrate derivative metabolic process [inference]

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

aminoglycoside antibiotic metabolic process [inference]

daunorubicin metabolic process

doxorubicin metabolic process

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

fructose biosynthetic process

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol biosynthetic process

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

primary alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

tertiary alcohol metabolic process [inference]

doxorubicin metabolic process

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

hexitol biosynthetic process [inference]

sorbitol biosynthetic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

stress-activated protein kinase signaling cascade

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

unsaturated fatty acid metabolic process [inference]

prostanoid metabolic process [inference]

prostaglandin metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

retinol metabolic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular developmental process [inference]

cell maturation [inference]

epithelial cell maturation

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

cellular response to methylglyoxal

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

cellular response to oxygen-containing compound [inference]

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to peptide

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

reproductive process [inference]

multicellular organismal reproductive process [inference]

maternal process involved in female pregnancy

multicellular organismal process [inference]

system process [inference]

renal system process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

epithelial cell maturation

anatomical structure development [inference]

tube development [inference]

collecting duct development [inference]

cellular developmental process [inference]

cell maturation [inference]

epithelial cell maturation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

hyperosmotic response [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to salt stress [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to abiotic stimulus [inference]

response to osmotic stress [inference]

hyperosmotic response [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to salt stress [inference]

hyperosmotic salinity response [inference]

cellular hyperosmotic salinity response

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

response to endogenous stimulus [inference]

response to hormone [inference]

response to thyroid hormone

cellular response to endogenous stimulus [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to thyroid hormone

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

response to peptide [inference]

cellular response to peptide

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

cellular response to methylglyoxal

cellular response to aldehyde [inference]

cellular response to methylglyoxal

response to ketone [inference]

response to methylglyoxal [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

cellular response to methylglyoxal

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

cellular response to oxygen-containing compound [inference]

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to peptide

cellular response to ketone [inference]

cellular response to methylglyoxal

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

response to peptide [inference]

cellular response to peptide

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

response to oxygen-containing compound [inference]

response to peptide [inference]

cellular response to peptide

response to ketone [inference]

response to methylglyoxal [inference]

cellular response to methylglyoxal

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to oxygen-containing compound [inference]

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to peptide

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

cellular response to organic substance [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

cellular response to methylglyoxal

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide

cellular response to oxygen-containing compound [inference]

cellular response to aldehyde [inference]

cellular response to methylglyoxal

cellular response to peptide

cellular response to ketone [inference]

cellular response to methylglyoxal

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

cellular response to salt stress [inference]

cellular hyperosmotic salinity response

cellular hyperosmotic response [inference]

cellular hyperosmotic salinity response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

stress-activated protein kinase signaling cascade

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinol metabolic process

regulation of body fluid levels [inference]

regulation of urine volume

multicellular organismal-level water homeostasis [inference]

renal water homeostasis

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
extracellular space	IDA	16332428
nucleoplasm	ISO
mitochondrion	ISO	34800366
cytosol	ISO
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm

cytosol

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

paranodal junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

glial cell projection [inference]

Schwann cell microvillus

actin-based cell projection [inference]

microvillus [inference]

Schwann cell microvillus

Schmidt-Lanterman incisure

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

mast cell granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

mast cell granule

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
retinal dehydrogenase activity	ISS
retinal dehydrogenase activity	ISO
alditol:NADP+ 1-oxidoreductase activity	ISO
alditol:NADP+ 1-oxidoreductase activity	IDA	2114645
alditol:NADP+ 1-oxidoreductase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

aldo-keto reductase (NADP) activity [inference]

alcohol dehydrogenase (NADP+) activity [inference]

glycerol dehydrogenase [NAD(P)+] activity [inference]

glycerol dehydrogenase [NADP+] activity

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

retinal dehydrogenase activity

glyceraldehyde oxidoreductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

aldo-keto

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
alditol
oxidoreductase activity

Displaying **all 4** entries
InterPro
Aldo-keto reductase
Aldo/keto reductase, conserved site
NADP-dependent oxidoreductase domain superfamily
NADP-dependent oxidoreductase domain

Alliance of Genome Resources

Expression

Displaying **all 7** entries
Location	References
Schmidt-Lanterman incisure	PMID:1650113
perinuclear region of cytoplasm	PMID:8150024
extracellular space	PMID:16332428
paranodal junction	PMID:1650113
plasma membrane bounded cell projection cytoplasm	PMID:8150024
Schwann cell microvillus	PMID:1650113
mast cell granule	PMID:1650113

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:1205	allergic disease	Alliance of Genome Resources
DOID:83	cataract	Alliance of Genome Resources
DOID:8947	diabetic retinopathy	Alliance of Genome Resources
DOID:9743	diabetic neuropathy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	231	Xenbase:XB-GENE-5821742	HUMAN91413
Saccharomyces cerevisiae S288C	1109	SGD:S000005646
Saccharomyces cerevisiae S288C	1645	SGD:S000005646
Saccharomyces cerevisiae S288C	1646	SGD:S000005646
Saccharomyces cerevisiae S288C	6718	SGD:S000005646
Saccharomyces cerevisiae S288C	8644	SGD:S000005646
Saccharomyces cerevisiae S288C	10327	SGD:S000005646
Mus musculus	11677	Xenbase:XB-GENE-5821742	MOUSE50461
Xenopus tropicalis	24192	Xenbase:XB-GENE-5821742
Xenopus tropicalis	39304	Xenbase:XB-GENE-5821742

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025