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Repository for lectin-assisted multimodality data
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MIRAGE
glutamate ionotropic receptor NMDA type subunit 2B
Summary
- Gene Symbol
-
- Grin2b
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Cytoskeleton
- Direct protein sequencing
- Disulfide bond
- Endosome
- Glycoprotein
- Ligand-gated ion channel
- Lysosome
- Magnesium
- Metal-binding
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| Q00960 |
|
| G3V746 |
|
| A0ABK0LAK0 |
|
| A6IMH0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of inhibitory postsynaptic potential | ||
| calcium ion transmembrane import into cytosol | ||
| calcium ion transmembrane import into cytosol | ||
| calcium ion transmembrane import into cytosol | ||
| monoatomic cation transmembrane transport |
GO Hierarchy
- rhythmic process
- response to nicotine
biological process
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamate binding | ||
| glutamate-gated calcium ion channel activity | ||
| glutamate-gated calcium ion channel activity | ||
| glutamate-gated calcium ion channel activity | ||
| D2 dopamine receptor binding |
GO Hierarchy
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
passive transmembrane transporter activity [inference]
channel activity [inference]
binding [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Glutamate receptor ionotropic
- Functional Category
-
- E: Amino acid transport and metabolism
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:1094 | attention deficit hyperactivity disorder | |
| DOID:224 | transient cerebral ischemia | |
| DOID:9279 | hyperhomocysteinemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2903 | Xenbase:XB-GENE-949327 | ||
| 2904 | Xenbase:XB-GENE-949327 | HUMAN11346 | |
| 2905 | FB:FBgn0053513 | ||
| 2906 | FB:FBgn0053513 | ||
| 14811 | Xenbase:XB-GENE-949327 | ||
| 14812 | Xenbase:XB-GENE-949327 | MOUSE49741 | |
| 14813 | FB:FBgn0053513 | ||
| 14814 | FB:FBgn0053513 | ||
| 24409 | Xenbase:XB-GENE-949327 | ||
| 24410 | Xenbase:XB-GENE-949327 |
