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MIRAGE
glutamate ionotropic receptor NMDA type subunit 2B
Summary
- Gene Symbol
-
- Grin2b
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Cytoskeleton
- Direct protein sequencing
- Disulfide bond
- Endosome
- Glycoprotein
- Ligand-gated ion channel
- Lysosome
- Magnesium
- Metal-binding
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| action potential | ||
| behavioral fear response | ||
| behavioral fear response | ||
| response to hypoxia | ||
| in utero embryonic development |
GO Hierarchy
- rhythmic process
- response to nicotine
biological process
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamatergic synapse | ||
| glutamatergic synapse | ||
| glutamatergic synapse | ||
| postsynaptic density, intracellular component |
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamate-gated receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity |
GO Hierarchy
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
passive transmembrane transporter activity [inference]
channel activity [inference]
binding [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- glutamate
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ligand-gated monoatomic ion channel activity |
| monoatomic ion transport |
| InterPro |
|---|
| Periplasmic binding protein-like I |
| Receptor, ligand binding region |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:1094 | attention deficit hyperactivity disorder | |
| DOID:224 | transient cerebral ischemia | |
| DOID:9279 | hyperhomocysteinemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 111223739 | SERDU22753 | ||
| 112146837 | ORYME17013 | ||
| 113021204 | ASTCA31113 | ||
| 113434312 | PSETE00099 | ||
| 113475853 | ATHCN06373 | ||
| 113589370 | ELEEL42600 | ||
| 113892509 | BOBOX39905 | ||
| 114038925 | VOMUR25183 | ||
| 114605053 | PODMU34767 | ||
| 115200387 | SALTR27343 |
