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MIRAGE
glutamate ionotropic receptor NMDA type subunit 2B
Summary
- Gene Symbol
-
- Grin2b
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Cytoskeleton
- Direct protein sequencing
- Disulfide bond
- Endosome
- Glycoprotein
- Ligand-gated ion channel
- Lysosome
- Magnesium
- Metal-binding
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| action potential | ||
| behavioral fear response | ||
| behavioral fear response | ||
| response to hypoxia | ||
| in utero embryonic development |
GO Hierarchy
- rhythmic process
- response to nicotine
biological process
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamatergic synapse | ||
| glutamatergic synapse | ||
| glutamatergic synapse | ||
| postsynaptic density, intracellular component |
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutamate-gated receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity | ||
| NMDA glutamate receptor activity |
GO Hierarchy
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
passive transmembrane transporter activity [inference]
channel activity [inference]
binding [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- glutamate
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ligand-gated monoatomic ion channel activity |
| monoatomic ion transport |
| InterPro |
|---|
| Periplasmic binding protein-like I |
| Receptor, ligand binding region |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:1094 | attention deficit hyperactivity disorder | |
| DOID:224 | transient cerebral ischemia | |
| DOID:9279 | hyperhomocysteinemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115605203 | STRHB22644 | ||
| 116442651 | CORMO20382 | ||
| 116834972 | CHEAB10651 | ||
| 117029473 | RHIFE10052 | ||
| 118239276 | CRIGR12739 | ||
| 118902207 | BALMU03245 | ||
| 122224274 | PANLE16636 | ||
| 123781746 | URSAM04675 |
