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polycystic kidney disease 1 like 3

Summary

Gene Symbol

Pkd1l3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

244646

PubChem

244646

Alliance of Genome Resources

MGI:2664670

Annotation

Keyword

3D-structure
Alternative splicing
Calcium transport
Cell membrane
Disulfide bond
Glycoprotein
Ion channel
Lectin
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2EG98	PC1-like 3 protein Polycystic kidney disease protein 1-like 3
A2A258

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
detection of chemical stimulus involved in sensory perception of sour taste	IDA IMP	16891422 20605874
calcium ion transport	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sour taste

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus

response to mechanical stimulus [inference]

detection of mechanical stimulus

response to abiotic stimulus [inference]

response to pH [inference]

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

detection of abiotic stimulus [inference]

detection of mechanical stimulus

response to mechanical stimulus [inference]

detection of mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus

detection of abiotic stimulus [inference]

detection of mechanical stimulus

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of sour taste

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of sour taste

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

calcium ion transport

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

organic substance transport [inference]

calcium ion transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IBA
receptor complex	IDA	16891422
plasma membrane	ISO ISS
cell surface	IDA	16891422
cation channel complex	IDA	16891422

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex

cellular anatomical entity [inference]

cell surface

plasma membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	16891422
monoatomic cation transmembrane transporter activity	IDA	16891422
calcium channel activity	IBA
transmembrane transporter binding	IPI	16891422
sour taste receptor activity	IDA IMP	16891422 20605874

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

calcium channel activity

monoatomic cation transmembrane transporter activity

monoatomic cation channel activity

calcium channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

calcium channel activity

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

binding [inference]

protein binding

transmembrane transporter binding

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

taste receptor activity [inference]

sour taste receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

polycystic kidney disease protein 1-like 3

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
calcium channel activity
calcium ion binding
detection of mechanical stimulus

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:898	autosomal dominant polycystic kidney disease	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 52 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Castor canadensis	109694283	51338_0:002fd7
Mus caroli	110300907	10089_0:002415
Mus pahari	110337351	10093_0:004387
Grammomys surdaster	114622128	491861_0:001417
Peromyscus leucopus	114708053	10041_0:001eaf
Mastomys coucha	116070150	35658_0:002d6e
Rattus rattus	116886055	10117_0:004c8b
Arvicanthis niloticus	117722984	61156_0:003d8b
Arvicola amphibius	119801738	1047088_0:004d6d
Microtus oregoni	121447332	111838_0:000bf9

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024