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polycystic kidney disease 1 like 3

Summary

Gene Symbol

Pkd1l3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

244646

PubChem

244646

Alliance of Genome Resources

MGI:2664670

Annotation

Keyword

3D-structure
Alternative splicing
Calcium transport
Cell membrane
Disulfide bond
Glycoprotein
Ion channel
Lectin
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2EG98	PC1-like 3 protein Polycystic kidney disease protein 1-like 3
A2A258

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
detection of chemical stimulus involved in sensory perception of sour taste	IDA IMP	16891422 20605874
calcium ion transport	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sour taste

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus

response to mechanical stimulus [inference]

detection of mechanical stimulus

response to abiotic stimulus [inference]

response to pH [inference]

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

detection of abiotic stimulus [inference]

detection of mechanical stimulus

response to mechanical stimulus [inference]

detection of mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus

detection of abiotic stimulus [inference]

detection of mechanical stimulus

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of sour taste

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of sour taste

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

calcium ion transport

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

organic substance transport [inference]

calcium ion transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IBA
receptor complex	IDA	16891422
plasma membrane	ISO ISS
cell surface	IDA	16891422
cation channel complex	IDA	16891422

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex

cellular anatomical entity [inference]

cell surface

plasma membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	16891422
monoatomic cation transmembrane transporter activity	IDA	16891422
calcium channel activity	IBA
transmembrane transporter binding	IPI	16891422
sour taste receptor activity	IDA IMP	16891422 20605874

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

calcium channel activity

monoatomic cation transmembrane transporter activity

monoatomic cation channel activity

calcium channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

calcium channel activity

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

binding [inference]

protein binding

transmembrane transporter binding

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

taste receptor activity [inference]

sour taste receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

polycystic kidney disease protein 1-like 3

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
calcium channel activity
calcium ion binding
detection of mechanical stimulus

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:898	autosomal dominant polycystic kidney disease	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of 52 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Dipodomys spectabilis	122126061	105255_0:003c79
Jaculus jaculus	123458630	51337_0:00052e
Perognathus longimembris pacificus	125357877	214514_0:002740
Myodes glareolus	125402301	447135_0:0013d3
Microtus fortis	126502477	100897_0:001812
Acomys russatus	127209267	60746_0:004176
Phodopus roborovskii	127234714	109678_0:003da3
Apodemus sylvaticus	127671536	10129_0:004eb0
Peromyscus californicus insignis	128103368	564181_0:004f95
Psammomys obesus	129687192	48139_1:003185

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024