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inhibin subunit alpha

Summary

Gene Symbol

Inha

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24504

PubChem

24504

Alliance of Genome Resources

RGD:2912

Annotation

Keyword

Cleavage on pair of basic residues
Disulfide bond
Glycoprotein
Growth factor
Hormone
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JW45
P17490

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
ovarian follicle development	IMP	18243599
signal transduction	IEA
male gonad development	IMP	9019274
regulation of cell population proliferation	ISO
hemoglobin biosynthetic process	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process [inference]

hemoglobin biosynthetic process

organonitrogen compound biosynthetic process [inference]

hemoglobin biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

organonitrogen compound biosynthetic process [inference]

hemoglobin biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process [inference]

hemoglobin biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

protein metabolic process [inference]

hemoglobin metabolic process [inference]

hemoglobin biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process [inference]

hemoglobin biosynthetic process

organonitrogen compound biosynthetic process [inference]

hemoglobin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

organonitrogen compound biosynthetic process [inference]

hemoglobin biosynthetic process

cellular process [inference]

signal transduction

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

hemoglobin biosynthetic process

reproductive process [inference]

developmental process involved in reproduction [inference]

ovarian follicle development

reproductive structure development [inference]

gonad development [inference]

male gonad development

developmental process [inference]

developmental process involved in reproduction [inference]

ovarian follicle development

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure development [inference]

ovarian follicle development

animal organ development [inference]

gonad development [inference]

male gonad development

reproductive structure development [inference]

gonad development [inference]

male gonad development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of hormone secretion [inference]

regulation of gonadotropin secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of follicle-stimulating hormone secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of gonadotropin secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of follicle-stimulating hormone secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of multicellular organismal process [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of cellular process [inference]

signal transduction

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of hormone secretion [inference]

regulation of gonadotropin secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of follicle-stimulating hormone secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of cell cycle

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of gonadotropin secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of follicle-stimulating hormone secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of endocrine process [inference]

regulation of gonadotropin secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of follicle-stimulating hormone secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of multicellular organismal process [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

regulation of gonadotropin secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

regulation of follicle-stimulating hormone secretion [inference]

negative regulation of follicle-stimulating hormone secretion

negative regulation of hormone secretion [inference]

negative regulation of gonadotropin secretion [inference]

negative regulation of follicle-stimulating hormone secretion

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment	IDA	7596220
photoreceptor inner segment	IDA	7596220
extracellular space	IDA	8014597
extracellular space	IBA
inhibin-betaglycan-ActRII complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

inhibin complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

inhibin-betaglycan-ActRII complex

cellular anatomical entity [inference]

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	ISO
cytokine activity	IBA
hormone activity	IEA
growth factor activity	IEA
inhibin binding	IPI	17636211 8994390

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

receptor ligand activity [inference]

inhibin binding

protein-containing complex binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

inhibin alpha chain

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
cytokine activity
growth factor activity

Displaying **all 5** entries
InterPro
Cystine-knot cytokine
Inhibin, alpha subunit
Transforming growth factor beta, conserved site
Transforming growth factor-beta, C-terminal
Transforming growth factor-beta-related

Alliance of Genome Resources

Expression

Displaying **all 6** entries
Location	References
inhibin A complex	PMID:8994390
inhibin B complex	PMID:17636211
photoreceptor inner segment	PMID:7596220
photoreceptor outer segment	PMID:7596220
neuronal cell body	PMID:10201810
extracellular space	PMID:8014597

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3623	Xenbase:XB-GENE-853910	HUMAN67172
Mus musculus	16322	Xenbase:XB-GENE-853910	MOUSE31002
Xenopus tropicalis	24504	Xenbase:XB-GENE-853910
Bos taurus	281254		BOVIN24815
Sus scrofa	397386		PIGXX10062
Canis lupus familiaris	488540		CANLF14264
Danio rerio	570520		DANRE39380
Macaca mulatta	574379		MACMU07007
Pan troglodytes	743866		PANTR29866
Monodelphis domestica	100009806		MONDO32552