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adhesion G protein-coupled receptor F5

Summary

Gene Symbol

Adgrf5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

245977

PubChem

245977

Alliance of Genome Resources

RGD:621679

Annotation

Keyword

Cell membrane
Direct protein sequencing
Disulfide bond
G-protein coupled receptor
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JJ39
Q9WVT0	G-protein coupled hepta-helical receptor Ig-hepta G-protein coupled receptor 116

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	PMID
glomerular filtration	ISO
glomerular filtration	IEA
energy reserve metabolic process	ISO
energy reserve metabolic process	IBA
energy reserve metabolic process	IEA

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

system process [inference]

renal system process [inference]

renal filtration [inference]

glomerular filtration

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis [inference]

pharyngeal arch artery morphogenesis

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphate metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

negative regulation of cellular process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphate metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA
cell surface	ISO
cell surface	IEA
cytoplasmic vesicle	ISO
cytoplasmic vesicle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

apical part of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Adhesion G protein-coupled receptor F5

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cell surface receptor signaling pathway
energy reserve metabolic process
fat cell differentiation
regulation of lipid metabolic process

Displaying **all 5** entries
InterPro
GAIN domain superfamily
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM
GPS motif
Immunoglobulin-like domain

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	77596	ZFIN:ZDB-GENE-041001-212
Danio rerio	78249	ZFIN:ZDB-GENE-041001-214
Danio rerio	221393	ZFIN:ZDB-GENE-041001-214
Homo sapiens	221395	Xenbase:XB-GENE-6468452	HUMAN85106
Mus musculus	224792	Xenbase:XB-GENE-6468452	MOUSE21840
Xenopus tropicalis	245977	Xenbase:XB-GENE-6468452
Danio rerio	266977	ZFIN:ZDB-GENE-041001-214
Danio rerio	435529	ZFIN:ZDB-GENE-041001-214
Canis lupus familiaris	474926		CANLF02819
Bos taurus	532674		BOVIN18611

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Acknowledgements