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BPI fold containing family A, member 1

Summary

Gene Symbol

Bpifa1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

246238

PubChem

246238

Alliance of Genome Resources

RGD:619818

Annotation

Keyword

Antibiotic
Disulfide bond
Glycoprotein
Innate immunity
Lipid-binding
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8K4I4	Palate lung and nasal epithelium clone protein
A6KHX6	Palate lung and nasal epithelium clone protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
immune response in nasopharyngeal-associated lymphoid tissue	ISO
immune response in nasopharyngeal-associated lymphoid tissue	IBA
positive regulation of acute inflammatory response	ISO
antibacterial humoral response	ISS
antibacterial humoral response	ISO

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

cellular process [inference]

cell killing [inference]

killing of cells of another organism

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of biological process involved in symbiotic interaction [inference]

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

positive regulation of biological process [inference]

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

positive regulation of acute inflammatory response

positive regulation of inflammatory response [inference]

positive regulation of acute inflammatory response

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of biological quality [inference]

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular region	ISS
extracellular region	ISO
extracellular space	ISS
extracellular space	ISO
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

Displaying 1 entry
GO Term	Evidence Code	PMID
lipid binding	IEA

GO Hierarchy

molecular function

binding [inference]

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

BPI fold-containing family A member 1

Functional Category

K: Transcription
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
antimicrobial humoral immune response mediated by antimicrobial peptide
immune response in nasopharyngeal-associated lymphoid tissue
lipid binding
negative regulation of single-species biofilm formation in or on host organism

Displaying **all 2** entries
InterPro
Bactericidal permeability-increasing protein, alpha/beta domain superfamily
Lipid-binding serum glycoprotein, N-terminal

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
microvillus	PMID:11821380

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	18843	HGNC:15749	MOUSE32047
Homo sapiens	51297		HUMAN56535
Homo sapiens	246238	HGNC:15749
Bos taurus	281989		BOVIN05101
Sus scrofa	449524		PIGXX11592
Pan troglodytes	458177		PANTR24643
Canis lupus familiaris	609982		CANLF09451
Macaca mulatta	714509		MACMU02894
Monodelphis domestica	100032873		MONDO08858
Callithrix jacchus	100406570		CALJA35320