mechanistic target of rapamycin kinase

Summary
Gene Symbol
  • MTOR
Organism
Homo sapiens (human)
NCBI Gene
2475
PubChem
2475
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Biological rhythms
  • Cytoplasm
  • Cytoplasmic vesicle
  • Disease variant
  • Epilepsy
  • Golgi apparatus
  • Intellectual disability
  • Lysosome
  • Microsome
  • Mitochondrion outer membrane
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
  • TPR repeat
Proteins
Displaying all 2 entries
UniProt Protein Name
A0A8V8TQ52
P42345
  • FK506-binding protein 12-rapamycin complex-associated protein 1
  • FKBP12-rapamycin complex-associated protein
  • Mammalian target of rapamycin
  • Mechanistic target of rapamycin
  • Rapamycin and FKBP12 target 1
  • Rapamycin target protein 1
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 30 in total
GO Term Evidence Code PMID
Golgi membrane
nucleus
nuclear envelope
nucleoplasm
cytoplasm
GO Hierarchy
GO Hierarchy
Disease
Disease Ontology
Displaying all 6 entries
DO ID Disease Name Source
DOID:10283 prostate cancer
DOID:2797 idiopathic interstitial pneumonia
DOID:5409 lung small cell carcinoma
DOID:8411 kidney angiomyolipoma
DOID:898 autosomal dominant polycystic kidney disease
DOID:9352 type 2 diabetes mellitus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025