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MIRAGE
C-C motif chemokine ligand 2
Summary
- Gene Symbol
-
- Ccl2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Chemotaxis
- Cytokine
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| positive regulation of leukocyte mediated cytotoxicity | ||
| positive regulation of endothelial cell proliferation | ||
| leukocyte migration involved in inflammatory response | ||
| chronic inflammatory response |
GO Hierarchy
- response to activity
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell cycle [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| endocytic vesicle |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor binding | ||
| cytokine activity | ||
| chemokine activity | ||
| chemokine activity | ||
| chemokine activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- C-C motif chemokine 2
- Functional Category
-
- K: Transcription
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell chemotaxis |
| chemokine activity |
| cytokine activity |
| eosinophil chemotaxis |
| immune response |
| InterPro |
|---|
| Chemokine beta/gamma/delta |
| Chemokine interleukin-8-like domain |
| Chemokine interleukin-8-like superfamily |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:10763 | hypertension | |
| DOID:10941 | intracranial aneurysm | |
| DOID:11713 | diabetic angiopathy | |
| DOID:13139 | crescentic glomerulonephritis | |
| DOID:13603 | obstructive jaundice | |
| DOID:224 | transient cerebral ischemia | |
| DOID:2799 | bronchiolitis obliterans | |
| DOID:2920 | membranoproliferative glomerulonephritis | |
| DOID:3082 | interstitial lung disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6347 | HGNC:10618 | ||
| 6369 | ZFIN:ZDB-GENE-041014-165 | ||
| 6376 | ZFIN:ZDB-GENE-041014-163 | ||
| 20292 | ZFIN:ZDB-GENE-110411-218 | ||
| 20296 | ZFIN:ZDB-GENE-110411-218 | MOUSE05361 | |
| 20306 | ZFIN:ZDB-GENE-041014-320 | ||
| 24770 | ZFIN:ZDB-GENE-041014-165 | ||
| 29397 | ZFIN:ZDB-GENE-041014-165 | ||
| 89808 | ZFIN:ZDB-GENE-041014-320 | ||
| 287561 | ZFIN:ZDB-GENE-041014-320 |
