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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
surfactant protein A1
Summary
- Gene Symbol
-
- Sftpa1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Collagen
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Hydroxylation
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Surface film
- Proteins
| UniProt | Protein Name |
|---|---|
| P08427 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to mechanical stimulus | ||
| response to vitamin A | ||
| cellular response to nitric oxide | ||
| circadian rhythm | ||
| response to hypoxia |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| multivesicular body | ||
| collagen trimer | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| carbohydrate binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- pulmonary surfactant-associated protein A
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| C-type lectin fold |
| C-type lectin, conserved site |
| C-type lectin-like/link domain superfamily |
| C-type lectin-like |
| Collectin, C-type lectin-like domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050127 | sinusitis | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:11396 | pulmonary edema | |
| DOID:11650 | bronchopulmonary dysplasia | |
| DOID:12120 | pulmonary alveolar proteinosis | |
| DOID:12716 | newborn respiratory distress syndrome | |
| DOID:1273 | respiratory syncytial virus infectious disease | |
| DOID:13406 | pulmonary sarcoidosis | |
| DOID:1485 | cystic fibrosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 20387 | 10090_1:004415 | MGI:109518 | MOUSE14335 | |
| 34019 | FB:FBgn0031910 | |||
| 53542 | FB:FBgn0040099 | |||
| 53543 | FB:FBgn0040104 | |||
| 397503 | PIGXX07906 | |||
| 407213 | BOVIN22632 | |||
| 443033 | SHEEP12935 | |||
| 466123 | PANTR01006 | |||
| 574108 | MACMU45150 | |||
| 653509 | HGNC:10798 | HUMAN01909 |
