GlyCosmos Portal

Annotation

Keyword

Alternative splicing
Direct protein sequencing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Lipid metabolism
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q64550	B1 UDP-glucuronosyltransferase 1-1
Q5DT04
Q547Q8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
liver development	IEP	16310220 18938141
bilirubin conjugation	TAS	11829457
xenobiotic metabolic process	ISO
xenobiotic metabolic process	IDA	8806713
acute-phase response	IEP	9737578

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

xenobiotic catabolic process [inference]

biphenyl catabolic process

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

pigment metabolic process [inference]

flavone metabolic process

hormone metabolic process [inference]

estrogen metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

benzene-containing compound metabolic process [inference]

biphenyl metabolic process [inference]

biphenyl catabolic process

xenobiotic metabolic process

xenobiotic catabolic process [inference]

biphenyl catabolic process

xenobiotic glucuronidation

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

xenobiotic catabolic process [inference]

biphenyl catabolic process

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

heterocycle metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

estrogen metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

lipid metabolic process [inference]

steroid metabolic process [inference]

estrogen metabolic process

flavonoid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

estrogen metabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

benzene-containing compound metabolic process [inference]

biphenyl metabolic process [inference]

biphenyl catabolic process

organic cyclic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

organonitrogen compound metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

organonitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

benzene-containing compound metabolic process [inference]

biphenyl metabolic process [inference]

biphenyl catabolic process

xenobiotic metabolic process

xenobiotic catabolic process [inference]

biphenyl catabolic process

xenobiotic glucuronidation

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

biphenyl catabolic process

xenobiotic catabolic process [inference]

biphenyl catabolic process

cellular nitrogen compound catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

heterocycle metabolic process [inference]

tetrapyrrole metabolic process [inference]

porphyrin-containing compound metabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

heterocycle catabolic process [inference]

tetrapyrrole catabolic process [inference]

porphyrin-containing compound catabolic process [inference]

bilirubin conjugation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration

animal organ development [inference]

animal organ regeneration

gland development [inference]

liver development

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

acute inflammatory response [inference]

acute-phase response

response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to steroid hormone

response to corticosteroid [inference]

response to glucocorticoid

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to chemical [inference]

response to nutrient

response to xenobiotic stimulus

cellular response to xenobiotic stimulus

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone [inference]

cellular response to hormone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to steroid hormone

response to corticosteroid [inference]

response to glucocorticoid

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

response to organic cyclic compound

response to estradiol [inference]

cellular response to estradiol stimulus

response to steroid hormone

response to corticosteroid [inference]

response to glucocorticoid

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

response to lipid [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

response to lipopolysaccharide

response to steroid hormone

response to corticosteroid [inference]

response to glucocorticoid

cellular response to glucocorticoid stimulus

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

response to alcohol [inference]

response to ethanol

cellular response to ethanol

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

response to oxygen-containing compound [inference]

response to estradiol [inference]

cellular response to estradiol stimulus

response to lipopolysaccharide

response to alcohol [inference]

response to ethanol

cellular response to ethanol

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus [inference]

cellular response to corticosteroid stimulus [inference]

cellular response to glucocorticoid stimulus

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to estradiol stimulus

cellular response to alcohol [inference]

cellular response to ethanol

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	ISO
endoplasmic reticulum	IDA	14561759
endoplasmic reticulum	IBA
endoplasmic reticulum membrane	IEA
plasma membrane	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

endoplasmic reticulum protein-containing complex [inference]

endoplasmic reticulum chaperone complex

catalytic complex [inference]

cytochrome complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
retinoic acid binding	ISO
enzyme inhibitor activity	ISO
steroid binding	ISO
glucuronosyltransferase activity	ISO
glucuronosyltransferase activity	IDA	11829457

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding [inference]

enzyme binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

steroid binding

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

organic cyclic compound binding [inference]

steroid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Glucuronosyltransferase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
UDP-glycosyltransferase activity
transferase activity

Displaying 1 entry
InterPro
UDP-glucuronosyl/UDP-glucosyltransferase

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cytochrome complex	PMID:17965520

Rhea

RHEA:21032

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:2741	bilirubin metabolic disorder	Alliance of Genome Resources
DOID:3803	Crigler-Najjar syndrome	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP012443
Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A1

Ortholog

Displaying entries **1 - 10** of **176** in total

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Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	7363	FB:FBgn0040260
Drosophila melanogaster	7364	FB:FBgn0040260
Drosophila melanogaster	7365	FB:FBgn0040260
Drosophila melanogaster	7366	FB:FBgn0040260
Drosophila melanogaster	7367	FB:FBgn0040260
Drosophila melanogaster	7368	FB:FBgn0040260
Drosophila melanogaster	10720	FB:FBgn0040260
Drosophila melanogaster	10941	FB:FBgn0040260
Xenopus tropicalis	22236	Xenbase:XB-GENE-998849
Caenorhabditis elegans	22238	WB:WBGene00015695

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements