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MIRAGE
follicle stimulating hormone receptor
Summary
- Gene Symbol
-
- FSHR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Leucine-rich repeat
- Reference proteome
- Repeat
- Signal
- Sulfation
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P23945 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor signaling pathway | ||
| adenylate cyclase-activating G protein-coupled receptor signaling pathway | ||
| spermatogenesis | ||
| female gamete generation | ||
| gonad development |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| membrane | ||
| receptor complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| follicle-stimulating hormone receptor activity | ||
| follicle-stimulating hormone receptor activity | ||
| follicle-stimulating hormone receptor activity | ||
| protein binding | ||
| G protein-coupled peptide receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- lutropin-choriogonadotropic hormone receptor
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled peptide receptor activity |
| hormone-mediated signaling pathway |
| protein-hormone receptor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080493 | ovarian dysgenesis 1 | |
| DOID:14450 | 46 XX gonadal dysgenesis | |
| DOID:5425 | ovarian hyperstimulation syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2492 | Xenbase:XB-GENE-986647 | ||
| 3973 | FB:FBgn0016650 | ||
| 7253 | FB:FBgn0016650 | ||
| 14309 | Xenbase:XB-GENE-986647 | MOUSE19877 | |
| 16867 | FB:FBgn0016650 | ||
| 22095 | FB:FBgn0016650 | ||
| 25360 | FB:FBgn0016650 | ||
| 25449 | Xenbase:XB-GENE-986647 | RATNO35059 | |
| 25477 | FB:FBgn0016650 | ||
| 195820 | DANRE04292 |
