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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
coagulation factor IX
Summary
- Gene Symbol
-
- F9
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Blood coagulation
- Calcium
- Disulfide bond
- EGF-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydroxylation
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Sulfation
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P16296 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| zymogen activation | ||
| blood coagulation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| endopeptidase activity | ||
| peptidase activity | ||
| calcium ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- coagulation factor IX
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| blood coagulation |
| calcium ion binding |
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| zymogen activation |
| InterPro |
|---|
| Peptidase S1A, coagulation factor VII/IX/X/C/Z |
| Serine proteases, trypsin domain |
| Serine proteases, trypsin family, histidine active site |
| Serine proteases, trypsin family, serine active site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080839 | X-linked warfarin sensitivity | |
| DOID:0111899 | X-linked thrombophilia due to factor IX defect | |
| DOID:12259 | hemophilia B | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 125343656 | 214514_0:004fac | |||
| 125415354 | 447135_0:0032c9 | |||
| 126512087 | 100897_0:00300f | |||
| 127184869 | 60746_0:004d81 | |||
| 127218119 | 109678_0:0010fe | |||
| 127675626 | 10129_0:005686 | |||
| 128116049 | 564181_0:000307 | |||
| 129671017 | 48139_0:004221 | |||
| 130868167 | 269649_0:0054d2 | |||
| 131899917 | 42410_0:0052e2 |
