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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
coagulation factor IX
Summary
- Gene Symbol
-
- F9
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Blood coagulation
- Calcium
- Disulfide bond
- EGF-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydroxylation
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Sulfation
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| P16296 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| zymogen activation | ||
| blood coagulation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| endopeptidase activity | ||
| peptidase activity | ||
| calcium ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- coagulation factor IX
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| blood coagulation |
| calcium ion binding |
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| zymogen activation |
| InterPro |
|---|
| Peptidase S1A, coagulation factor VII/IX/X/C/Z |
| Serine proteases, trypsin domain |
| Serine proteases, trypsin family, histidine active site |
| Serine proteases, trypsin family, serine active site |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080839 | X-linked warfarin sensitivity | |
| DOID:0111899 | X-linked thrombophilia due to factor IX defect | |
| DOID:12259 | hemophilia B | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 102146175 | MACFA45259 | |||
| 102174637 | CAPHI31161 | |||
| 102357491 | LATCH17450 | |||
| 102429338 | MYOLU00661 | |||
| 102463532 | PELSI16793 | |||
| 102913042 | 230844_0:00512c | |||
| 103022627 | ASTMX18531 | |||
| 103232665 | CHLSB18821 | |||
| 103264135 | CARSF25585 | |||
| 103672846 | URSMA23334 |
