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Guidelines

MIRAGE

calcitonin receptor like receptor

Summary

Gene Symbol

Calcrl

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25029

KEGG Gene ID

PubChem

25029

Alliance of Genome Resources

RGD:2255

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q63118	Calcitonin receptor-like receptor
A6HMP9	Calcitonin receptor-like receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
angiogenesis	ISO
angiogenesis	IBA
calcium ion transport	ISO
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

calcitonin family receptor signaling pathway [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

animal organ development [inference]

heart development

response to stimulus [inference]

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to disaccharide [inference]

response to sucrose [inference]

cellular response to sucrose stimulus

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport

protein transport

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of smooth muscle cell proliferation

positive regulation of vascular associated smooth muscle cell proliferation

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

calcitonin family receptor signaling pathway [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of smooth muscle cell proliferation

positive regulation of vascular associated smooth muscle cell proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation

positive regulation of vascular associated smooth muscle cell proliferation

regulation of vascular associated smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of smooth muscle cell proliferation

positive regulation of vascular associated smooth muscle cell proliferation

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of smooth muscle contraction [inference]

negative regulation of smooth muscle contraction

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
lysosome	ISO
endosome	ISO
endoplasmic reticulum	ISO
plasma membrane	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

adrenomedullin receptor complex

calcitonin family receptor complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

G protein-coupled receptor complex [inference]

G protein-coupled receptor dimeric complex [inference]

adrenomedullin receptor complex

calcitonin family receptor complex [inference]

cellular anatomical structure [inference]

cytoplasm

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

exocytic vesicle [inference]

synaptic vesicle

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
adrenomedullin receptor activity	ISO
adrenomedullin receptor activity	IBA
calcitonin gene-related peptide receptor activity	ISO
calcitonin gene-related peptide receptor activity	IBA
transmembrane signaling receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

hormone binding [inference]

peptide hormone binding [inference]

calcitonin family binding [inference]

adrenomedullin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

calcitonin family receptor activity [inference]

transmembrane signaling receptor activity

G protein-coupled receptor activity

G protein-coupled peptide receptor activity [inference]

calcitonin family receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	10203	HGNC:16709
Danio rerio	445508	ZFIN:ZDB-GENE-040822-26
Xenopus tropicalis	549647	Xenbase:XB-GENE-5736126
Mus musculus	54598	MGI:1926944
Caenorhabditis elegans	175942	WB:WBGene00015735

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026