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polymeric immunoglobulin receptor

Summary

Gene Symbol

Pigr

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25046

PubChem

25046

Alliance of Genome Resources

RGD:3328

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P15083

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
detection of chemical stimulus involved in sensory perception of bitter taste	ISO
detection of chemical stimulus involved in sensory perception of bitter taste	IEA
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	ISS
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	ISO
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

vesicle-mediated transport [inference]

transcytosis [inference]

immunoglobulin transcytosis in epithelial cells [inference]

immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

multicellular organismal process [inference]

transcytosis [inference]

immunoglobulin transcytosis in epithelial cells [inference]

immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor

response to stimulus [inference]

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of bitter taste

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of bitter taste

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

transcytosis [inference]

immunoglobulin transcytosis in epithelial cells [inference]

immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

regulation of response to stimulus [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

regulation of cellular process [inference]

signal transduction

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	ISO
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

immunoglobulin complex [inference]

immunoglobulin complex, circulating [inference]

IgA immunoglobulin complex, circulating [inference]

polymeric IgA immunoglobulin complex [inference]

secretory IgA immunoglobulin complex

IgA immunoglobulin complex [inference]

IgA immunoglobulin complex, circulating [inference]

polymeric IgA immunoglobulin complex [inference]

secretory IgA immunoglobulin complex

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

recycling endosome membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

recycling endosome membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
polymeric immunoglobulin binding	ISO
polymeric immunoglobulin binding	IEA
polymeric immunoglobulin receptor activity	ISO
polymeric immunoglobulin receptor activity	IEA
transmembrane signaling receptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

growth factor receptor binding [inference]

epidermal growth factor receptor binding

protein-containing complex binding [inference]

immunoglobulin binding [inference]

polymeric immunoglobulin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

immunoglobulin receptor activity [inference]

polymeric immunoglobulin receptor activity

immune receptor activity [inference]

immunoglobulin receptor activity [inference]

polymeric immunoglobulin receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

polymeric immunoglobulin receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
InterPro
Immunoglobulin V-set domain
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
recycling endosome membrane	PMID:10468577

Ortholog

Displaying entries **1 - 10** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5284	Xenbase:XB-GENE-981188	HUMAN54500
Danio rerio	10871	ZFIN:ZDB-GENE-080303-2
Danio rerio	11314	ZFIN:ZDB-GENE-080303-2
Mus musculus	18703	Xenbase:XB-GENE-981188	MOUSE28444
Xenopus tropicalis	25046	Xenbase:XB-GENE-981188
Danio rerio	52685	ZFIN:ZDB-GENE-150409-8
Danio rerio	64435	ZFIN:ZDB-GENE-150409-2
Danio rerio	83953	ZFIN:ZDB-GENE-150409-8
Danio rerio	140497	ZFIN:ZDB-GENE-060503-327
Danio rerio	146722	ZFIN:ZDB-GENE-080303-2