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MIRAGE
estrogen receptor 2
Summary
- Gene Symbol
-
- Esr2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- DNA-binding
- Glycoprotein
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Steroid-binding
- Transcription regulation
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A9K3Y725 |
|
| Q59IV8 |
|
| Q62986 |
|
| A0A9K3Y862 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| ovarian follicle development | ||
| ovarian follicle development |
GO Hierarchy
biological process
cellular process [inference]
reproductive process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA-binding transcription activator activity, RNA polymerase II-specific | ||
| DNA binding | ||
| nuclear steroid receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Estrogen receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| estrogen response element binding |
| metal ion binding |
| nuclear steroid receptor activity |
| sequence-specific DNA binding |
| steroid binding |
| zinc ion binding |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:10763 | hypertension | |
| DOID:1596 | depressive disorder | |
| DOID:1612 | breast cancer | |
| DOID:2030 | anxiety disorder | |
| DOID:219 | colon cancer | |
| DOID:224 | transient cerebral ischemia | |
| DOID:6432 | pulmonary hypertension | |
| DOID:8283 | peritonitis | |
| DOID:8634 | prostate carcinoma in situ |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2100 | HUMAN19773 | ||
| 13983 | Xenbase:XB-GENE-486256 | MOUSE09157 | |
| 25149 | Xenbase:XB-GENE-486256 | ||
| 281146 | BOVIN01541 | ||
| 396697 | PIGXX15301 | ||
| 403639 | CANLF17989 | ||
| 443066 | SHEEP18372 | ||
| 452964 | PANTR08943 | ||
| 574110 | MACMU42479 | ||
| 100027583 | MONDO04545 |
