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Glucuronyltransferase I

Summary

Gene Symbol

GlcAT-I

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

251900

KEGG Gene ID

dme:Dmel_CG32775

PubChem

251900

Alliance of Genome Resources

FB:FBgn0066114

Annotation

Keyword

Glycoprotein
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O97422	Beta-1,3-glucuronyltransferase I Glucuronosyltransferase I UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase
B5RJ22

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
chondroitin sulfate proteoglycan biosynthetic process	IBA
protein glycosylation
proteoglycan biosynthetic process	NAS	12511570
carbohydrate metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

chondroitin sulfate proteoglycan biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA
Golgi membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
metal ion binding
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	IBA IDA IEA	12511570

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity [inference]

galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity [inference]

galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
chondroitin sulfate proteoglycan biosynthetic process
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
metal ion binding
transferase activity

Displaying **all 2** entries
InterPro
Glycosyl transferase, family 43
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K10158

Name

galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05928	2.4.1.135	G87877ES	G14371GV

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
membrane	FB:FBrf0231198

Rhea

RHEA:24168

UDP-α-D-glucuronate

H⁺ + UDP

Enzyme

2.4.1.135

PMID

RHEA:56508

UDP-α-D-glucuronate

H⁺ + UDP

Enzyme

2.4.1.135

PMID

18400750

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080575	Larsen-like syndrome B3GAT3 type	Alliance of Genome Resources
DOID:3770	pulmonary fibrosis	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources
DOID:9206	Barrett's esophagus	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP008942
Gene Name: CG32775 gene product from transcript CG32775-RA

Ortholog

Displaying entries **41 - 50** of 55 in total

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Species	Gene ID	OrthoDB
Drosophila arizonae	108618593	7263_0:0019ff
Drosophila navojoa	108657103	7232_1:00256d
Drosophila serrata	110181804	7274_0:001b55
Drosophila obscura	111076068	7282_0:0032b1
Drosophila hydei	111593289	7224_1:001946
Drosophila novamexicana	115768366	47314_0:002b71
Drosophila mauritiana	117147739	7226_1:00344f
Drosophila albomicans	117577608	7291_1:0006eb
Drosophila guanche	117590791	7266_1:003032
Drosophila innubila	117793285	198719_1:002c2c

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GlyComb

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UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements