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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
branched chain keto acid dehydrogenase E1 subunit alpha
Summary
- Gene Symbol
-
- Bckdha
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Magnesium
- Metal-binding
- Mitochondrion
- Oxidoreductase
- Phosphoprotein
- Potassium
- Reference proteome
- Thiamine pyrophosphate
- Transit peptide
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| branched-chain amino acid catabolic process | ||
| response to nutrient | ||
| response to glucocorticoid | ||
| response to cAMP |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| oxoglutarate dehydrogenase complex | ||
| mitochondrion | ||
| mitochondrial matrix |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
- Functional Category
-
- C: Energy production and conversion
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| branched-chain amino acid catabolic process |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| oxidoreductase activity |
| InterPro |
|---|
| Dehydrogenase, E1 component |
| Thiamin diphosphate-binding fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9269 | maple syrup urine disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 593 | HGNC:986 | HUMAN43771 | ||
| 12039 | 10090_1:00230b | MGI:107701 | MOUSE51327 | |
| 41149 | FB:FBgn0037709 | |||
| 176716 | WB:WBGene00012713 | |||
| 468889 | PANTR18376 | |||
| 554124 | ZFIN:ZDB-GENE-050522-376 | DANRE13554 | ||
| 704978 | MACMU18826 | |||
| 100019333 | MONDO25091 | |||
| 100036656 | Xenbase:XB-GENE-1007472 | |||
| 100068678 | HORSE01764 |
