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milk fat globule EGF and factor V/VIII domain containing

Summary

Gene Symbol

Mfge8

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25277

PubChem

25277

Alliance of Genome Resources

RGD:3083

Annotation

Keyword

Angiogenesis
Cell adhesion
Cytoplasmic vesicle
Disulfide bond
EGF-like domain
Fertilization
Glycoprotein
Membrane
Proteomics identification
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P70490	MFGM Milk fat globule-EGF factor 8 O-acetyl GD3 ganglioside synthase SED1
A6JC45
Q1PBJ1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IEP	11085522
apoptotic cell clearance	IEA ISO
response to estrogen	IEP	12801995
cell adhesion	IEA
single fertilization	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

reproductive process [inference]

fertilization [inference]

single fertilization

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to estrogen

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

import into cell [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA ISO
acrosomal membrane	IEA
extracellular space	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

secretory granule membrane [inference]

acrosomal membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
integrin binding	IEA ISO
phosphatidylserine binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylserine binding

protein-containing complex binding [inference]

integrin binding

modified amino acid binding [inference]

phosphatidylserine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

lactadherin

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
InterPro
Coagulation factor 5/8 C-terminal domain
EGF-like domain
Galactose-binding-like domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:13375	temporal arteritis	Alliance of Genome Resources

Ortholog

Displaying entries **101 - 110** of **122** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Onychomys torridus	118582480	38674_0:000084
Balaenoptera musculus	118890863		BALMU29183
Arvicola amphibius	119802623	1047088_0:004543
Microtus oregoni	121453439	111838_0:000118
Dipodomys spectabilis	122123978	105255_0:0037ff
Cyprinus carpio carpio	122135584		CYPCA142327
Ursus americanus	123802428		URSAM29029
Marmota monax	124087905	9995_0:0007c1
Sciurus carolinensis	124976098	30640_0:000cff
Perognathus longimembris pacificus	125368080	214514_0:0040ad

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements