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milk fat globule EGF and factor V/VIII domain containing

Summary

Gene Symbol

Mfge8

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25277

PubChem

25277

Alliance of Genome Resources

RGD:3083

Annotation

Keyword

Angiogenesis
Cell adhesion
Cytoplasmic vesicle
Disulfide bond
EGF-like domain
Fertilization
Glycoprotein
Membrane
Proteomics identification
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P70490	MFGM Milk fat globule-EGF factor 8 O-acetyl GD3 ganglioside synthase SED1
A6JC45
Q1PBJ1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IEP	11085522
apoptotic cell clearance	IEA ISO
response to estrogen	IEP	12801995
cell adhesion	IEA
single fertilization	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

reproductive process [inference]

fertilization [inference]

single fertilization

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to estrogen

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

import into cell [inference]

endocytosis [inference]

phagocytosis [inference]

apoptotic cell clearance

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA ISO
acrosomal membrane	IEA
extracellular space	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

acrosomal membrane

bounding membrane of organelle [inference]

secretory granule membrane [inference]

acrosomal membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
integrin binding	IEA ISO
phosphatidylserine binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylserine binding

protein-containing complex binding [inference]

integrin binding

modified amino acid binding [inference]

phosphatidylserine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

lactadherin

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
InterPro
Coagulation factor 5/8 C-terminal domain
EGF-like domain
Galactose-binding-like domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:13375	temporal arteritis	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of **122** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Macaca fascicularis	102134091		MACFA38497
Peromyscus maniculatus bairdii	102923243	230844_0:000665
Astyanax mexicanus	103044962		ASTMX14491
Astyanax mexicanus	103047215		ASTMX17228
Nannospalax galili	103749918	1026970_0:003fe9	NANGA09436
Serinus canaria	103816073		SERCA10423
Rhinopithecus roxellana	104661609		RHIRO28617
Fukomys damarensis	104860151	885580_0:0009a5
Pteropus vampyrus	105305194		PTEVA09328
Macaca nemestrina	105488341		MACNE37561

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements