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fucosyltransferase 7

Summary

Gene Symbol

FUT7

Aliases

alpha (1,3) fucosyltransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

2529

GGDB ID

gg007

HGNC

4018

mRNA

NM_004479

map

9q34.3

Protein

NP_004470

OMIM

602030

KEGG Gene ID

hsa:2529

PubChem

2529

Alliance of Genome Resources

HGNC:4018

JoGo

FUT7

TogoVar

FUT7

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Proteomics identification
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q11130	Fucosyltransferase 7 Fucosyltransferase VII Galactoside 3-L-fucosyltransferase Selectin ligand synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
regulation of type IV hypersensitivity	ISS
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
leukocyte migration involved in immune response
leukocyte migration involved in inflammatory response	ISS
sphingolipid metabolic process	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte migration involved in immune response

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

T cell activation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

T cell activation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

metabolic process [inference]

catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

L-fucose catabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

L-fucose catabolic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

L-fucose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

L-fucose catabolic process

lipid metabolic process [inference]

sphingolipid metabolic process

ceramide metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

L-fucose catabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

L-fucose catabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

lymphocyte migration into lymphoid organs [inference]

lymphocyte migration into lymph node

reproductive process [inference]

embryo implantation

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

T cell activation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

regulatory T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

regulation of immune effector process [inference]

regulation of leukocyte mediated immunity [inference]

regulation of lymphocyte mediated immunity [inference]

regulation of T cell mediated immunity [inference]

regulation of type IV hypersensitivity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of insulin receptor signaling pathway

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cellular process [inference]

positive regulation of cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of insulin receptor signaling pathway

regulation of response to external stimulus [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response [inference]

regulation of acute inflammatory response [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of inflammatory response to antigenic stimulus [inference]

regulation of acute inflammatory response to antigenic stimulus [inference]

regulation of hypersensitivity [inference]

regulation of type IV hypersensitivity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of insulin receptor signaling pathway

regulation of cell adhesion [inference]

regulation of cell-cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion

positive regulation of cell-cell adhesion

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell

positive regulation of leukocyte tethering or rolling

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cell adhesion molecule production

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling

positive regulation of leukocyte tethering or rolling

regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of neutrophil migration

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IEA
Golgi apparatus	TAS
Golgi apparatus	IDA
trans-Golgi network	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
fucosyltransferase activity	IDA
fucosyltransferase activity	IEA
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	IDA
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity

alpha-(1->3)-fucosyltransferase activity

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

GlycoGene Database (GGDB)

GGDB ID

gg007

Gene Symbol

FUT7

Reactions

Displaying **all 3** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
GDP-Fuc	G22418PV	R	G19619KS	R	9461592
GDP-Fuc	G00065MO	R	G00054MO	R	8207002
GDP-Fuc	G31119YY	R	G51911JA	R	10622713

Displaying **all 3** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
GDP-Fuc	G22418PV	R	G19619KS	R	9461592
GDP-Fuc	G00065MO	R	G00054MO	R	8207002
GDP-Fuc	G31119YY	R	G51911JA	R	10622713 9461592

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Donor	Acceptor	Reducing terminal(Acceptor)	Reference
GDP-Fuc	G78941GA	Free	8182079
GDP-Fuc	G00050MO	Free	8182079
GDP-Fuc	G46055MA	2AB	11278338
GDP-Fuc	G00049MO	Free	8182079
GDP-Fuc	G95098GZ	Free	8182079

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	NP_955785	NM_199491
Mus musculus	NP_038552	NM_013524

KEGG BRITE Database

Orthology

K07635

Name

galactoside alpha-1,3-fucosyltransferase 7 [EC:2.4.1.-]

References

8207002

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06075	2.4.1.- 2.4.1.65	G01767JJ	G96401FK

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000249
Gene Name: fucosyltransferase 7 (alpha (1,3) fucosyltransferase)

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	562250	ZFIN:ZDB-GENE-060929-997
Xenopus laevis	108698150	Xenbase:XB-GENE-6487292
Mus musculus	14347	MGI:107692
Rattus norvegicus	296564	RGD:735019
Caenorhabditis elegans	188084	WB:WBGene00020222
Caenorhabditis elegans	187342	WB:WBGene00001507
Caenorhabditis elegans	3565968	WB:WBGene00043986
Drosophila melanogaster	39653	FB:FBgn0036485

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements