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cytochrome c oxidase subunit 5A

Summary

Gene Symbol

Cox5a

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

252934

PubChem

252934

Alliance of Genome Resources

RGD:620607

Annotation

Keyword

Acetylation
Direct protein sequencing
Heme
Mitochondrion inner membrane
Phosphoprotein
Reference proteome
Transit peptide
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P11240	Cytochrome c oxidase polypeptide Va
A6J4V5	Cytochrome c oxidase polypeptide Va

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrial electron transport, cytochrome c to oxygen	IBA
mitochondrial electron transport, cytochrome c to oxygen	IEA
proton transmembrane transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, cytochrome c to oxygen

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrial inner membrane	ISO
mitochondrial inner membrane	IEA
mitochondrial membrane	ISO
respiratory chain complex IV	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

respiratory chain complex [inference]

respiratory chain complex IV

catalytic complex [inference]

cytochrome complex [inference]

respiratory chain complex IV

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytochrome-c oxidase activity	TAS	2544858
cytochrome-c oxidase activity	IDA	7601105
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

electron transfer activity [inference]

cytochrome-c oxidase activity

oxidoreductase activity, acting on a heme group of donors [inference]

cytochrome-c oxidase activity

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

cytochrome-c oxidase activity

active monoatomic ion transmembrane transporter activity [inference]

cytochrome-c oxidase activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

cytochrome-c oxidase activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

oxidoreduction-driven active transmembrane transporter activity [inference]

cytochrome-c oxidase activity

active monoatomic ion transmembrane transporter activity [inference]

cytochrome-c oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytochrome C oxidase

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
metal ion binding
mitochondrial electron transport, cytochrome c to oxygen
oxidative phosphorylation

Displaying **all 2** entries
InterPro
Cytochrome c oxidase, subunit Va/VI superfamily
Cytochrome c oxidase, subunit Va/VI

Ortholog

Displaying entries **1 - 10** of 30 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9377		HUMAN24269
Xenopus tropicalis	12858	Xenbase:XB-GENE-973617
Xenopus tropicalis	252934	Xenbase:XB-GENE-973617
Pan troglodytes	453750		PANTR10820
Macaca mulatta	692061		MACMU41223
Ciona intestinalis	100181337		CIOIN02909
Taeniopygia guttata	100218354		TAEGU02387
Callithrix jacchus	100401281		CALJA00325
Pongo abelii	100459812		PONAB06772
Pongo abelii	100461926		PONAB09640