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adenosine A2a receptor

Summary

Gene Symbol

Adora2a

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25369

PubChem

25369

Alliance of Genome Resources

RGD:2049

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P30543
A6JKL4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 53 in total

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GO Term	Evidence Code	PMID
synaptic transmission, dopaminergic	ISO
G protein-coupled adenosine receptor signaling pathway	ISO
G protein-coupled adenosine receptor signaling pathway	IDA	12590138
G protein-coupled adenosine receptor signaling pathway	IBA
response to amphetamine	ISO

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

glial cell activation [inference]

astrocyte activation

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

apoptotic signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

multicellular organismal process [inference]

cell activation [inference]

glial cell activation [inference]

astrocyte activation

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

regulation of vascular permeability [inference]

negative regulation of vascular permeability

blood vessel diameter maintenance [inference]

vasodilation

renal system process [inference]

regulation of urine volume [inference]

positive regulation of urine volume

behavior [inference]

locomotory behavior

feeding behavior [inference]

eating behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

response to stimulus [inference]

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to organonitrogen compound [inference]

response to purine-containing compound

response to caffeine

response to amine [inference]

response to amphetamine

response to alkaloid

response to caffeine

response to organic cyclic compound [inference]

response to purine-containing compound

response to caffeine

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound

response to caffeine

response to amine [inference]

response to amphetamine

response to alkaloid

response to caffeine

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

presynaptic modulation of chemical synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amine transport [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of amine transport [inference]

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

positive regulation of amine transport [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of amino acid transport [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of circadian rhythm [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of circadian rhythm [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of circadian rhythm [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amine transport [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of amino acid transport [inference]

positive regulation of glutamate secretion

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell population proliferation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

regulation of inflammatory response [inference]

negative regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

apoptotic signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, cholinergic [inference]

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

presynaptic modulation of chemical synaptic transmission

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of apoptotic signaling pathway

positive regulation of synaptic transmission [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of synaptic transmission, cholinergic [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell population proliferation

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phosphorylation [inference]

negative regulation of protein phosphorylation [inference]

negative regulation of protein kinase activity

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of glutamate secretion [inference]

positive regulation of glutamate secretion

regulation of neurotransmitter secretion [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of acetylcholine secretion, neurotransmission [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of neurotransmitter secretion [inference]

positive regulation of acetylcholine secretion, neurotransmission

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, sleep [inference]

positive regulation of circadian sleep/wake cycle, sleep

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of lymphocyte activation [inference]

regulation of T cell activation [inference]

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

positive regulation of multicellular organismal process [inference]

positive regulation of behavior [inference]

positive regulation of circadian sleep/wake cycle, sleep

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of T cell activation [inference]

negative regulation of alpha-beta T cell activation

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential [inference]

regulation of vascular permeability [inference]

negative regulation of vascular permeability

regulation of synaptic plasticity [inference]

regulation of long-term synaptic potentiation [inference]

positive regulation of long-term synaptic potentiation

regulation of body fluid levels [inference]

regulation of urine volume [inference]

positive regulation of urine volume

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasodilation

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

regulation of protein kinase activity [inference]

negative regulation of protein kinase activity

negative regulation of transferase activity [inference]

negative regulation of kinase activity [inference]

negative regulation of protein kinase activity

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS
intermediate filament	IDA	16644907
plasma membrane	ISO
plasma membrane	IDA	23994616
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

plasma membrane region [inference]

cell projection membrane [inference]

neuron projection membrane [inference]

axolemma

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

glutamatergic synapse

neuron to neuron synapse [inference]

asymmetric synapse

leading edge membrane [inference]

neuron projection membrane [inference]

axolemma

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

cell body [inference]

neuronal cell body

presynaptic active zone

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
G protein-coupled adenosine receptor activity	ISO
G protein-coupled adenosine receptor activity	TAS	12189203
G protein-coupled adenosine receptor activity	IDA	12590138
G protein-coupled adenosine receptor activity	IBA
protein binding	IPI	16617164 17356572 23994616

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

G protein-coupled glutamate receptor binding [inference]

type 5 metabotropic glutamate receptor binding

glutamate receptor binding [inference]

G protein-coupled glutamate receptor binding [inference]

type 5 metabotropic glutamate receptor binding

calmodulin binding

cytoskeletal protein binding [inference]

actinin binding [inference]

alpha-actinin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled adenosine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Adenosine receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Alliance of Genome Resources

Expression

Displaying **all 9** entries
Location	References
presynaptic active zone	PMID:16481441
intermediate filament	PMID:16644907
neuronal cell body	PMID:16644907
axolemma	PMID:16481441
asymmetric synapse	PMID:16481441
dendrite	PMID:16952160
postsynaptic membrane	PMID:16481441
axon	PMID:16952160
presynaptic membrane	PMID:16481441

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:850	lung disease	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	134	FB:FBgn0039747
Homo sapiens	135	Xenbase:XB-GENE-970783	HUMAN59609
Drosophila melanogaster	136	FB:FBgn0039747
Drosophila melanogaster	140	FB:FBgn0039747
Drosophila melanogaster	11539	FB:FBgn0039747
Mus musculus	11540	Xenbase:XB-GENE-970783	MOUSE02270
Drosophila melanogaster	11541	FB:FBgn0039747
Xenopus tropicalis	25369	Xenbase:XB-GENE-970783
Drosophila melanogaster	29290	FB:FBgn0039747
Drosophila melanogaster	29316	FB:FBgn0039747

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements