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thiazole biosynthetic enzyme

Summary

Gene Symbol

thi2

Organism

Schizosaccharomyces pombe (fission yeast)

External Links

NCBI Gene: 2540526
PubChem: 2540526

Annotation

Keyword

Cytoplasm
Iron
Metal-binding
NAD
Nucleus
Reference proteome
Thiamine biosynthesis
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
P40998	Thiazole biosynthetic enzyme

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
thiamine biosynthetic process	IMP	1868574 7992507
thiazole biosynthetic process	IMP	1868574
thiazole biosynthetic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

oxazole or thiazole metabolic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic substance biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

thiazole biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

oxazole or thiazole metabolic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	HDA	16823372
mitochondrion
cytosol	HDA	16823372

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
iron ion binding	IBA
pentosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

THIAMINE THIAZOLE SYNTHASE

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
iron ion binding
metal ion binding
pentosyltransferase activity
thiamine biosynthetic process
thiazole biosynthetic process
transferase activity

Displaying **all 3** entries
InterPro
FAD/NAD(P)-binding domain superfamily
Thiamine thiazole synthase
Thiazole biosynthetic enzyme Thi4 family

Rhea

RHEA:55708

glycine + NAD⁺

ADP-5-ethyl-4-methylthiazole-2-carboxylate + H₂O + H⁺ + nicotinamide

Enzyme

2.4.2.60

PMID

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements