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Nem1-Spo7 phosphatase complex catalytic subunit Nem1

Summary

Gene Symbol

nem1

Organism

Schizosaccharomyces pombe (fission yeast)

External Links

NCBI Gene: 2541021
PubChem: 2541021

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Nucleus
Protein phosphatase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O59718

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
lipid storage	IMP	30116786
signaling	NAS
negative regulation of phospholipid biosynthetic process	ISO
nuclear membrane organization	IMP	30116786

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

nuclear membrane organization

localization [inference]

maintenance of location [inference]

lipid storage

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phosphate metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

signaling

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phosphorus metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phosphate metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of phosphorus metabolic process [inference]

negative regulation of phosphate metabolic process [inference]

negative regulation of phospholipid metabolic process [inference]

negative regulation of phospholipid biosynthetic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	IDA	30116786
endoplasmic reticulum	HDA	16823372
endoplasmic reticulum membrane
nuclear membrane
Nem1-Spo7 phosphatase complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

Nem1-Spo7 phosphatase complex

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

Nem1-Spo7 phosphatase complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein serine/threonine phosphatase activity	IBA
myosin phosphatase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

myosin phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein serine/threonine phosphatase activity

myosin phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying 1 entry
Gene Ontology
phosphoprotein phosphatase activity

Displaying **all 4** entries
InterPro
Dullard phosphatase domain, eukaryotic
FCP1 homology domain
HAD superfamily
HAD-like superfamily

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Last updated: April 6, 2026

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