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laminin subunit beta 2

Summary

Gene Symbol

Lamb2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25473

PubChem

25473

Alliance of Genome Resources

RGD:2988

Annotation

Keyword

3D-structure
Basement membrane
Cell adhesion
Coiled coil
Disulfide bond
Glycoprotein
Laminin EGF-like domain
Phosphoprotein
Reference proteome
Repeat
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6I359
P15800	Laminin chain B3 Laminin-11 subunit beta Laminin-14 subunit beta Laminin-15 subunit beta Laminin-3 subunit beta Laminin-4 subunit beta Laminin-7 subunit beta Laminin-9 subunit beta S-laminin subunit beta
M0R6K0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
cell morphogenesis	ISO
Schwann cell development	IEA ISO
retina development in camera-type eye	IEA ISO
basement membrane assembly	IBA
neuromuscular junction development	IEA ISO

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

cell growth [inference]

developmental cell growth [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension [inference]

axon extension involved in regeneration

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

glomerular epithelial cell development [inference]

podocyte development [inference]

metanephric podocyte development

metanephric glomerular epithelial cell development [inference]

metanephric podocyte development

glial cell development [inference]

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

extracellular matrix assembly [inference]

basement membrane assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

synapse organization

neuromuscular junction development

extracellular structure organization [inference]

extracellular matrix organization [inference]

glomerular basement membrane development [inference]

metanephric glomerular basement membrane development

basement membrane organization [inference]

basement membrane assembly

extracellular matrix assembly [inference]

basement membrane assembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

glomerular basement membrane development [inference]

metanephric glomerular basement membrane development

basement membrane organization [inference]

basement membrane assembly

extracellular matrix assembly [inference]

basement membrane assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

developmental process [inference]

anatomical structure morphogenesis [inference]

anatomical structure development [inference]

tissue development

glomerular basement membrane development [inference]

metanephric glomerular basement membrane development

cell development [inference]

epithelial cell development [inference]

glomerular epithelial cell development [inference]

podocyte development [inference]

metanephric podocyte development

metanephric glomerular epithelial cell development [inference]

metanephric podocyte development

glial cell development [inference]

retina development in camera-type eye

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

glomerular epithelial cell development [inference]

podocyte development [inference]

metanephric podocyte development

metanephric glomerular epithelial cell development [inference]

metanephric podocyte development

glial cell development [inference]

growth [inference]

cell growth [inference]

developmental cell growth [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension [inference]

axon extension involved in regeneration

developmental growth [inference]

developmental cell growth [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension [inference]

axon extension involved in regeneration

developmental growth involved in morphogenesis [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension [inference]

axon extension involved in regeneration

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
laminin complex	IBA ISO
neuromuscular junction	IEA ISO
basement membrane	ISO
laminin-3 complex	IEA ISO
synaptic cleft	IEA ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

laminin complex

laminin-3 complex

cellular anatomical entity [inference]

extracellular region [inference]

synaptic cleft

cell junction [inference]

synapse

neuromuscular junction

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix [inference]

basement membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
integrin binding	IBA IEA ISO
structural constituent of synapse-associated extracellular matrix	IBA IEA ISO

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent [inference]

structural constituent of synapse-associated extracellular matrix

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

laminin subunit beta-2

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
animal organ morphogenesis
substrate adhesion-dependent cell spreading
tissue development

Displaying **all 4** entries
InterPro
EGF-like domain
Laminin IV type B
Laminin, N-terminal
Laminin-type EGF domain

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0060852	Pierson syndrome	Alliance of Genome Resources
DOID:0080380	nephrotic syndrome type 5	Alliance of Genome Resources
DOID:1070	primary open angle glaucoma	Alliance of Genome Resources
DOID:2527	nephrosis	Alliance of Genome Resources
DOID:576	proteinuria	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **102** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3913		HGNC:6487	HUMAN70002
Mus musculus	16779	10090_1:002f72	MGI:99916	MOUSE62322
Caenorhabditis elegans	177292		WB:WBGene00002247
Danio rerio	337767		ZFIN:ZDB-GENE-081030-4	DANRE24165
Pan troglodytes	460365			PANTR31116
Canis lupus familiaris	476626			CANLF07516
Bos taurus	520167			BOVIN17855
Macaca mulatta	707892			MACMU29498
Oryctolagus cuniculus	100009388			RABIT12823
Monodelphis domestica	100027514			MONDO29473

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements