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proprotein convertase subtilisin/kexin type 6

Summary

Gene Symbol

Pcsk6

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25507

PubChem

25507

Alliance of Genome Resources

RGD:3246

Annotation

Keyword

Calcium
Cleavage on pair of basic residues
Glycoprotein
Reference proteome
Repeat
Serine protease
Signal
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q63415	Paired basic amino acid cleaving enzyme 4 Subtilisin-like proprotein convertase 4 Subtilisin/kexin-like protease PACE4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 16 in total

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GO Term	Evidence Code	PMID
glycoprotein metabolic process	ISO
glycoprotein metabolic process	IEA
protein processing	ISO
peptide hormone processing	ISO
peptide hormone processing	IEP	8070361

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

glycoprotein metabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

hormone metabolic process [inference]

peptide hormone processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

glycoprotein metabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

glycoprotein metabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

glycoprotein metabolic process

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

cellular process [inference]

export from cell [inference]

secretion by cell

multicellular organismal process [inference]

pattern specification process [inference]

axis specification [inference]

embryonic axis specification [inference]

anterior/posterior axis specification, embryo [inference]

zygotic determination of anterior/posterior axis, embryo

anterior/posterior axis specification [inference]

anterior/posterior axis specification, embryo [inference]

zygotic determination of anterior/posterior axis, embryo

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

embryonic pattern specification [inference]

embryonic axis specification [inference]

anterior/posterior axis specification, embryo [inference]

zygotic determination of anterior/posterior axis, embryo

neurotrophin production [inference]

nerve growth factor production

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell

export from cell [inference]

secretion by cell

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IBA
extracellular space	IEA
cell surface	ISO
cell surface	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
endopeptidase activity	ISO
serine-type endopeptidase activity	ISO
serine-type endopeptidase activity	IBA
serine-type endopeptidase activity	IEA
heparin binding	ISO