GlyCosmos Portal

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GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IEA
inward rectifying potassium channel	ISS
inward rectifying potassium channel	ISO
inward rectifying potassium channel	IDA	24114458

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

inward rectifying potassium channel

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

inward rectifying potassium channel

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

potassium ion-transporting ATPase complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

inward rectifying potassium channel

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

potassium ion-transporting ATPase complex

cellular anatomical entity [inference]

membrane

plasma membrane

sarcolemma

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

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GO Term	Evidence Code	PMID
potassium channel activity	ISS
potassium channel activity	ISO
ATP binding	ISO
ATP binding	IEA
sulfonylurea receptor activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity

ATPase-coupled monoatomic cation transmembrane transporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

binding [inference]

protein binding [inference]

transmembrane transporter binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

ADP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

sulfonylurea receptor activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

multidrug resistance-associated

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
sarcolemma	PMID:15647111
synaptic vesicle membrane	PMID:14645230
inward rectifying potassium channel	PMID:24114458

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0060319	cardiac arrest	Alliance of Genome Resources
DOID:3525	middle cerebral artery infarction	Alliance of Genome Resources
DOID:4724	brain edema	Alliance of Genome Resources
DOID:9993	hypoglycemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6833	ZFIN:ZDB-GENE-050517-22	HUMAN04841
Drosophila melanogaster	10060	FB:FBgn0028675
Mus musculus	20927	ZFIN:ZDB-GENE-120215-45	MOUSE55542
Drosophila melanogaster	20928	FB:FBgn0028675
Danio rerio	25559	ZFIN:ZDB-GENE-050517-22
Drosophila melanogaster	25560	FB:FBgn0028675
Pan troglodytes	451056		PANTR02399
Canis lupus familiaris	485402		CANLF08576
Bos taurus	538996		BOVIN06676
Danio rerio	553281		DANRE27521

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Annotation

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Acknowledgements