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alkaline phosphatase, biomineralization associated

Summary

Gene Symbol

Alpl

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25586

PubChem

25586

Alliance of Genome Resources

RGD:2100

Annotation

Keyword

Biomineralization
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
GPI-anchor
Hydrolase
Magnesium
Metal-binding
Mitochondrion
Phosphoprotein
Reference proteome
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P08289	Alkaline phosphatase liver/bone/kidney isozyme Phosphoamidase Phosphocreatine phosphatase
A6ITE7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 20** of 24 in total

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GO Term	Evidence Code	PMID
phosphate ion homeostasis	ISO
calcium ion homeostasis	ISO
cellular response to organic cyclic compound
cementum mineralization	IEP	17043865
positive regulation of cold-induced thermogenesis	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

organonitrogen compound metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

pyridoxal phosphate metabolic process

cellular aromatic compound metabolic process [inference]

pyridoxal phosphate metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

pyridoxal phosphate metabolic process

organophosphate metabolic process [inference]

pyridoxal phosphate metabolic process

cellular nitrogen compound metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

heterocycle metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

small molecule metabolic process [inference]

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

pyridoxal phosphate metabolic process

organophosphate metabolic process [inference]

pyridoxal phosphate metabolic process

organic cyclic compound metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

organonitrogen compound metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

organic hydroxy compound metabolic process [inference]

pyridoxal phosphate metabolic process

futile creatine cycle

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

pyridoxal phosphate metabolic process

cellular aromatic compound metabolic process [inference]

pyridoxal phosphate metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

pyridoxal phosphate metabolic process

organophosphate metabolic process [inference]

pyridoxal phosphate metabolic process

cellular nitrogen compound metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

heterocycle metabolic process [inference]

pyridine-containing compound metabolic process [inference]

vitamin B6 metabolic process [inference]

pyridoxal phosphate metabolic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound

reproductive process [inference]

developmental process involved in reproduction

multicellular organismal process [inference]

ossification [inference]

replacement ossification [inference]

endochondral ossification

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

inhibition of non-skeletal tissue mineralization

developmental process [inference]

developmental process involved in reproduction

anatomical structure development [inference]

tissue development [inference]

biomineral tissue development

bone mineralization

tooth mineralization [inference]

cementum mineralization

homeostatic process [inference]

cellular homeostasis

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

inhibition of non-skeletal tissue mineralization

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

calcium ion homeostasis

inorganic ion homeostasis [inference]

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organonitrogen compound [inference]

response to vitamin B6

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to organic cyclic compound

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

cellular response to organic cyclic compound

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to cytokine [inference]

response to macrophage colony-stimulating factor

cellular response to organic substance [inference]

cellular response to organic cyclic compound

response to inorganic substance [inference]

response to sodium phosphate

response to antibiotic

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to vitamin B6

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to salt [inference]

response to sodium phosphate

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of cold-induced thermogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
extracellular space	IDA	19697513
mitochondrial intermembrane space	ISS
mitochondrial intermembrane space	ISO
plasma membrane	ISO
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

organelle membrane [inference]

mitochondrial membrane

external encapsulating structure [inference]

extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle envelope lumen [inference]

mitochondrial intermembrane space

organelle [inference]

membrane-bounded organelle [inference]

extracellular membrane-bounded organelle

extracellular organelle [inference]

extracellular membrane-bounded organelle

side of membrane

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
alkaline phosphatase activity	ISO
alkaline phosphatase activity	TAS	3422431
alkaline phosphatase activity	IDA	3472490
alkaline phosphatase activity	IBA
inorganic diphosphate phosphatase activity	IEA