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neuronal growth regulator 1

Summary

Gene Symbol

NEGR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

257194

PubChem

257194

Alliance of Genome Resources

HGNC:17302

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Disulfide bond
GPI-anchor
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7Z3B1	IgLON family member 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 15 in total

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GO Term	Evidence Code	PMID
brain development	IEA
feeding behavior	IEA
neuron projection development
positive regulation of calcium-mediated signaling	IEA
regulation of synapse assembly	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

lipid droplet organization [inference]

lipid droplet formation

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

lipid droplet formation

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

lipid droplet formation

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development

multicellular organismal process [inference]

behavior [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

anatomical structure development [inference]

animal organ development [inference]

brain development

muscle organ development [inference]

skeletal muscle organ development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of saliva secretion [inference]

positive regulation of saliva secretion

positive regulation of secretion [inference]

positive regulation of saliva secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of saliva secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of saliva secretion

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of saliva secretion

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

regulation of synapse organization [inference]

regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cell junction assembly [inference]

regulation of synapse assembly

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of digestive system process [inference]

regulation of saliva secretion [inference]

positive regulation of saliva secretion

positive regulation of digestive system process [inference]

positive regulation of saliva secretion

positive regulation of multicellular organismal process [inference]

positive regulation of digestive system process [inference]

positive regulation of saliva secretion

regulation of biological quality [inference]

regulation of body fluid levels [inference]

regulation of saliva secretion [inference]

positive regulation of saliva secretion

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
postsynaptic density	IEA
neuronal cell body	IEA
plasma membrane	TAS
side of membrane	IEA
extracellular region	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

postsynaptic specialization [inference]

postsynaptic density

cell body [inference]

neuronal cell body

side of membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	21982860 27940359 37207277

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

opioid-binding protein/cell adhesion molecule

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
InterPro
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **51 - 60** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Ictalurus punctatus	108272183		ICTPU02128
Rhinopithecus bieti	108522694		RHIBE26785
Xenopus laevis	108715513	Xenbase:XB-GENE-17334372
Cyprinus carpio carpio	109047850		CYPCA47946
Cyprinus carpio carpio	109053267		CYPCA56317
Electrophorus electricus	113570423		ELEEL08440
Bos indicus x Bos taurus	113889733		BOBOX06460
Podarcis muralis	114598853		PODMU05674
Echeneis naucrates	115041785		ECHNA36195
Salmo trutta	115157943		SALTR108198