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solute carrier family 24 member 2

Summary

Gene Symbol

SLC24A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

25769

PubChem

25769

Alliance of Genome Resources

HGNC:10976

Annotation

Keyword

Alternative splicing
Antiport
Calcium transport
Cell membrane
Glycoprotein
Phosphoprotein
Potassium transport
Reference proteome
Repeat
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UI40	Na(+)/K(+)/Ca(2+)-exchange protein 2 Retinal cone Na-Ca+K exchanger Solute carrier family 24 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 19 in total

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GO Term	Evidence Code	PMID
establishment of localization in cell	IEA
cone photoresponse recovery
calcium ion import across plasma membrane	IDA	10662833
monoatomic ion transmembrane transport	IDA	18166528
memory	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

phototransduction

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to light intensity [inference]

cellular response to high light intensity

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

behavior [inference]

learning or memory [inference]

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

neuron cellular homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

phototransduction

response to light intensity [inference]

response to high light intensity [inference]

cellular response to high light intensity

cellular response to light intensity [inference]

cellular response to high light intensity

cone photoresponse recovery

cellular response to light stimulus [inference]

cellular response to light intensity [inference]

cellular response to high light intensity

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to light intensity [inference]

cellular response to high light intensity

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to light intensity [inference]

cellular response to high light intensity

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to light intensity [inference]

cellular response to high light intensity

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport [inference]

sodium ion transmembrane transport

calcium ion transport [inference]

calcium ion import

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

potassium ion transmembrane transport

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

potassium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

organic substance transport [inference]

calcium ion transport [inference]

calcium ion import

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of cellular process [inference]

signal transduction [inference]

phototransduction

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

long-term synaptic potentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of synaptic transmission [inference]

long-term synaptic depression

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
presynapse	IEA
plasma membrane	IBA IDA RCA TAS	26631410
postsynapse	IEA
photoreceptor inner segment	ISS	10662833

GO Hierarchy

cellular component

cellular anatomical entity [inference]

photoreceptor inner segment

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium, potassium:sodium antiporter activity	IBA IDA TAS	10662833 18166528 26631410 27093457
symporter activity	IEA
calcium channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

sodium ion transmembrane transporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

sodium ion transmembrane transporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity

antiporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

sodium ion transmembrane transporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

calcium:monoatomic cation antiporter activity [inference]

calcium:sodium antiporter activity [inference]

calcium, potassium:sodium antiporter activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **71 - 80** of 84 in total

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Species	Gene ID	Orthologous MAtrix
Bos indicus x Bos taurus	113897000	BOBOX31742
Vombatus ursinus	114040887	VOMUR23639
Podarcis muralis	114587641	PODMU24244
Salmo trutta	115194088	SALTR91652
Salmo trutta	115198626	SALTR66071
Gadus morhua	115529756	GADMO20605
Sparus aurata	115590585	SPAAU08630
Strigops habroptila	115601109	STRHB08250
Corvus moneduloides	116437900	CORMO28221
Chelonoidis abingdonii	116835078	CHEAB08918

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