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galactosylceramidase

Summary

Gene Symbol

GALC

Aliases

Krabbe disease

Organism

Homo sapiens (human)

External Links

NCBI Gene

2581

HGNC

4115

KEGG Gene ID

hsa:2581

PubChem

2581

Alliance of Genome Resources

HGNC:4115

Annotation

Keyword

Alternative splicing
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Glycosidase
Leukodystrophy
Lipid degradation
Lysosome
Reference proteome
Signal
Sphingolipid metabolism

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0A0MQV0	Galactosylceramidase
P54803	Galactocerebroside beta-galactosidase Galactosylceramidase Galactosylceramide beta-galactosidase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
myelination	IEA
glycosphingolipid catabolic process	TAS
galactosylceramide catabolic process	IBA IDA ISS	8399327

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process [inference]

galactosylceramide catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process [inference]

galactolipid catabolic process [inference]

galactosylceramide catabolic process

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

sphingolipid catabolic process [inference]

glycosphingolipid catabolic process

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

ceramide catabolic process [inference]

glycosylceramide catabolic process [inference]

galactosylceramide catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lysosomal lumen	TAS
lysosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying 1 entry
GO Term	Evidence Code	PMID
galactosylceramidase activity	IBA IDA ISS TAS	8281145 8399327

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

galactosylceramidase activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000054983

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K01202

Name

galactosylceramidase [EC:3.2.1.46]

References

8281145

Rhea

H₂O + a β-D-galactosyl-(1↔1ʼ)-N-acylsphing-4-enine

D-galactose + an N-acylsphing-4-enine

Enzyme

3.2.1.46

PMID

Disease

Disease Ontology

Displaying entries **21 - 30** of 82 in total

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DO ID	Disease Name	Source
DOID:11771	spontaneous ocular nystagmus	DisGeNET
DOID:11832	visual epilepsy	DisGeNET
DOID:11934	head and neck cancer	DisGeNET
DOID:11949	Creutzfeldt-Jakob disease	Alliance of Genome Resources
DOID:12139	dysthymic disorder	DisGeNET
DOID:1289	neurodegenerative disease	DisGeNET
DOID:13034	relapsing fever	DisGeNET DisGeNET
DOID:13174	dissociated nystagmus	DisGeNET
DOID:1324	lung cancer	DisGeNET DisGeNET
DOID:1325	bronchus cancer	DisGeNET

The Human Phenotype Ontology

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HPO ID	HPO Term
HP:0000639	Nystagmus
HP:0000648	Optic atrophy
HP:0000649	Abnormality of visual evoked potentials
HP:0000712	Emotional lability
HP:0000737	Irritability
HP:0000762	Decreased nerve conduction velocity
HP:0001053	Hypopigmented skin patches
HP:0001250	Seizure
HP:0001251	Ataxia
HP:0001252	Hypotonia

Displaying **all 4** entries
Disease ID	Disease Name
ORPHA:206443	late-infantile/juvenile Krabbe disease
ORPHA:206448	adult Krabbe disease
ORPHA:206436	infantile Krabbe disease
OMIM:245200	Krabbe disease

PubChem Disease

GHR Health Conditions

Krabbe disease

MedGen Diseases

Galactosylceramide beta-galactosidase deficiency

OMIM Phenotypes

KRABBE DISEASE; KRB

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002432
Gene Name: galactosylceramidase

Ortholog

Displaying entries **71 - 80** of 84 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Nomascus leucogenys	100587134		NOMLE20592
Podarcis muralis	114591297		PODMU07399
Sinocyclocheilus grahami	107560205		SINGR75759
Sinocyclocheilus grahami	107583495		SINGR01025
Sinocyclocheilus grahami	107588298		SINGR42918
Equus asinus asinus	106834294		EQUAS06176
Echeneis naucrates	115035789		ECHNA39143
Salarias fasciatus	115406968		SALFA11375
Salarias fasciatus	115406969		SALFA11383
Athene cunicularia	113480749		ATHCN07419

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Last updated: August 19, 2024