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MIRAGE
sodium leak channel, non-selective
Summary
- Gene Symbol
-
- NALCN
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Coiled coil
- Disease variant
- Disulfide bond
- Glycoprotein
- Neurodegeneration
- Proteomics identification
- Reference proteome
- Repeat
- Sodium channel
- Transmembrane helix
- Voltage-gated channel
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A6Q8PF19 |
|
| Q8IZF0 |
|
| A0A6Q8PFS9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of synaptic transmission, cholinergic | ||
| positive regulation of synaptic transmission, GABAergic | ||
| ion transmembrane transport | ||
| monoatomic ion transmembrane transport | ||
| sodium ion transmembrane transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| monoatomic ion channel complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel activity | ||
| voltage-gated sodium channel activity | ||
| monoatomic cation channel activity | ||
| monoatomic cation channel activity | ||
| sodium channel activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081048 | congenital limbs-face contractures-hypotonia-developmental delay syndrome |
